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Protective Role of ATP-Sensitive Potassium Channels in Hypoxia-Induced Generalized Seizure
Adenosine triphosphate (ATP)–sensitive potassium (KATP) channels are activated by various metabolic stresses, including hypoxia. The substantia nigra pars reticulata (SNr), the area with the highestExpand
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Dynamic transformation of Bergmann glial fibers proceeds in correlation with dendritic outgrowth and synapse formation of cerebellar Purkinje cells
Bergmann glia (BG) are unipolar cerebellar astrocytes, whose radial (or Bergmann) fibers associate with developing granule cells and mature Purkinje cells (PCs). In the present study, we investigatedExpand
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A proteinase-storing body that prepares for cell death or stresses in the epidermal cells of Arabidopsis.
Plants degrade cellular materials during senescence and under various stresses. We report that the precursors of two stress-inducible cysteine proteinases, RD21 and a vacuolar processing enzymeExpand
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Acetyl-CoA carboxylase in higher plants: most plants other than gramineae have both the prokaryotic and the eukaryotic forms of this enzyme.
The presence and the absence of a prokaryote type and a eukaryote type of acetyl-CoA carboxylase (EC; ACCase) were examined in members of 28 plant families by two distinct methods: theExpand
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Role of nitric oxide in learning and memory and in monoamine metabolism in the rat brain
1 We investigated the effects of NG‐nitro‐L‐arginine methyl ester (L‐NAME), an inhibitor of nitric oxide (NO) synthase, on the performance of rats in a radial arm maze and in habituation tasks, andExpand
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Animal models of Alzheimer's disease and evaluation of anti-dementia drugs.
Alzheimer's disease (AD) is the most common cause of progressive decline of cognitive function in aged humans, and is characterized by the presence of numerous senile plaques and neurofibrillaryExpand
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Concurrent use of granulocyte colony-stimulating factor with low-dose cytosine arabinoside and aclarubicin for previously treated acute myelogenous leukemia: a pilot study.
We used a new chemotherapy regimen for the treatment of 18 consecutive patients with relapsed AML (median age 44 years, range 18-74). The regimen consisted of low-dose cytosine arabinoside (10Expand
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EAAT4 is a post-synaptic glutamate transporter at Purkinje cell synapses.
To study cellular and subcellular localizations of the glutamate transporter EAAT4, antibody was raised against the N-terminal peptide. On immunoblotting the antibody recognized a band in membraneExpand
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Cloning and characterization of gonadotropin-inducible ovarian transcription factors (GIOT1 and -2) that are novel members of the (Cys)(2)-(His)(2)-type zinc finger protein family.
Gonadotropins are essential for ovarian follicular development and differentiation. To identify genes that are rapidly induced by gonadotropin in the immature rat ovary, ovarian genes were screenedExpand
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Low superoxide dismutase activity in schizophrenic patients with tardive dyskinesia.
BACKGROUND Tardive dyskinesia (TD) is a therapy-resistant adverse effect of neuroleptics. Although the exact pathophysiology of TD is unknown, oxygen radicals have been speculated to play a role inExpand
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