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Loxoscelism: old obstacles, new directions.
TLDR
Animal model studies suggest the potential value of specific antivenom to decrease lesion size and limit systemic illness even when such administration is delayed. Expand
The Global Snake Bite Initiative: an antidote for snake bite
TLDR
The burden of human suffering caused by snake bite remains un-recognised, invisible, and unheard by the global public health community, forgotten by development agencies and governments alike. Expand
Enzymatic characterization, antigenic cross-reactivity and neutralization of dermonecrotic activity of five Loxosceles spider venoms of medical importance in the Americas.
TLDR
As Brazilian commercial antivenoms are able to neutralize the dermonecrosis induced by Loxosceles venoms of diverse geographical origin, clinical studies should be undertaken on the potential for a single global LoxOSceles antivenom. Expand
Phospholipase A2 in cnidaria.
TLDR
The current observations support the idea that cnidarian PLA2 may participate in the sting site irritation and systemic envenomation syndrome resulting from contact with cNidarians. Expand
Australian carybdeid jellyfish causing "Irukandji syndrome".
TLDR
Large knowledge gaps exist in biology of the jellyfish, their distribution, their toxins and mode of actions and in treatment of the Irukandji syndrome. Expand
Biology and ecology of Irukandji jellyfish (Cnidaria: Cubozoa).
TLDR
This work synthesise and contextualise available information on Irukandji taxonomy, phylogeny, reproduction, vision, behaviour, feeding, distribution, seasonality, toxins, and safety, and identifies major gaps in knowledge for future research. Expand
Immunological and toxinological responses to jellyfish stings.
TLDR
It is postulate that immunologically, both tubular structural and functional biopolymers as well as venom components can initiate innate, adaptive, aswell as immediate and delayed hypersensitivity reactions that may be amenable to topical anti-inflammatory-immunomodifier therapy. Expand
Ending the drought: new strategies for improving the flow of affordable, effective antivenoms in Asia and Africa.
TLDR
Two mechanisms through which the Global Snakebite Initiative might seek to end the antivenom drought in Africa and Asia are proposed: first by establishing a multidisciplinary, multicentre, international collaboration to evaluate currently available antivenoms against the venoms of medically important snakes from specific nations in Asia using a combination of proteomic, antivenomic and WHO-endorsed preclinical assessment protocols, to provide a validated evidence base for either recommending or rejecting individual products. Expand
CARDIOVASCULAR ACTIONS OF THE VENOM FROM THE IRUKANDJI (CARUKIA BARNESI) JELLYFISH: EFFECTS IN HUMAN, RAT AND GUINEA‐PIG TISSUES IN VITRO AND IN PIGS IN VITRO
TLDR
The cardiovascular pharmacology of the crude venom extract from the potentially lethal, very small carybdeid jellyfish Carukia barnesi is investigated in rat, guinea‐pig and human isolated tissues and anaesthetized piglets. Expand
Marine Stingers: Review of an Under-Recognized Global Coastal Management Issue
Dangerous marine stingers (jellyfish) are an emotive issue in tropical Australia, where they are widely regarded as the number one marine health threat. However, numerous severe and fatal stings haveExpand
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