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Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data
Correspondence of the brain's functional architecture during activation and rest
- Stephen M. Smith, P. Fox, C. Beckmann
- BiologyProceedings of the National Academy of Sciences
- 4 August 2009
Neural connections, providing the substrate for functional networks, exist whether or not they are functionally active at any given moment. However, it is not known to what extent brain regions are…
Differential effects of early hippocampal pathology on episodic and semantic memory.
- F. Vargha-Khadem, D. Gadian, K. Watkins, A. Connelly, W. van Paesschen, M. Mishkin
- Psychology, BiologyScience
- 18 July 1997
Global anterograde amnesia is described in three patients with brain injuries that occurred in one case at birth, in another by age 4, and in the third at age 9. Magnetic resonance techniques…
Structural and functional abnormalities of the motor system in developmental stuttering.
- K. Watkins, Stephen M. Smith, S. Davis, P. Howell
- Biology, LinguisticsBrain : a journal of neurology
- 10 October 2007
The data support the conclusion that stuttering is a disorder related primarily to disruption in the cortical and subcortical neural systems supporting the selection, initiation and execution of motor sequences necessary for fluent speech production.
Anatomically related grey and white matter abnormalities in adolescent-onset schizophrenia.
- G. Douaud, Stephen M. Smith, A. James
- Psychology, MedicineBrain : a journal of neurology
- 1 September 2007
Investigation of structural grey and white matter abnormalities in adolescent-onset schizophrenia found striking abnormalities in the primary sensorimotor and premotor cortices and in white matter tracts susbserving motor control, suggesting a new potential marker of altered white matter maturation specific to adolescent-ONSet schizophrenia.
Structural asymmetries in the human brain: a voxel-based statistical analysis of 142 MRI scans.
A voxel-wise statistical analysis of hemispheric asymmetries in regional 'amounts' of gray matter based on MRI scans obtained in 142 healthy young adults confirmed the presence of left-greater-than-right asymmetry in several posterior language areas and found previously described asymmetry in the cingulate sulcus and the caudate nucleus.
Seeing and hearing speech excites the motor system involved in speech production
Neural basis of an inherited speech and language disorder.
- F. Vargha-Khadem, K. Watkins, R. Passingham
- BiologyProceedings of the National Academy of Sciences…
- 13 October 1998
The genetic mutation or deletion in this region has resulted in the abnormal development of several brain areas that appear to be critical for both orofacial movements and sequential articulation, leading to marked disruption of speech and expressive language.
Behavioural analysis of an inherited speech and language disorder: comparison with acquired aphasia.
- K. Watkins, N. Dronkers, F. Vargha-Khadem
- Psychology, BiologyBrain : a journal of neurology
- 1 March 2002
Investigations of the KE family, half the members of which are affected by a severe disorder of speech and language, are reported, suggesting that, in the affected family members, the verbal and non-verbal deficits arise from a common impairment in the ability to sequence movement or in procedural learning.