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Isoflavone Aglycon Produced by Culture of Soybean Extracts with Basidiomycetes and Its Anti-angiogenic Activity
- T. Miura, L. Yuan, +4 authors K. Kosuna
- Biology, Medicine
- Bioscience, biotechnology, and biochemistry
- 1 January 2002
Soybean extracts (SBE) containing isoflavone glycosides were cultured with Ganoderma lucidum mycelia producing β-glucosidase. The anti-angiogenic effects of the cultivated product, containing rich in… Expand
The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents.
- B. Sun, K. Wakame, E. Sato, Hiroshi Nishioka, O. Aruoma, H. Fujii
- Cancer epidemiology
- 1 October 2009
BACKGROUND Active hexose correlated compound (AHCC) (a mixture of polysaccharides, amino acids, lipids and minerals derived from cultured mycelia of a Basidiomycete mushroom, Lentinula edodes) was… Expand
Acute, subchronic and genotoxicity studies conducted with Oligonol, an oligomerized polyphenol formulated from lychee and green tea extracts.
- H. Fujii, Hiroshi Nishioka, K. Wakame, B. Magnuson, Ashley Nicole Roberts
- Chemistry, Medicine
- Food and chemical toxicology : an international…
- 1 December 2008
Oligonol is a phenolic product derived from lychee fruit extract and green tea extract, containing catechin-type monomers and oligomers of proanthocyanidins, produced by a manufacturing process which… Expand
Suppressive effect of active hexose correlated compound (AHCC) on thymic apoptosis induced by dexamethasone in the rat.
- R. B. Burikhanov, K. Wakame, Y. Igarashi, S. Wang, S. Matsuzaki
- Biology, Medicine
- Endocrine regulations
- 1 December 2000
OBJECTIVE Mushroom extracts are known to have immunomodulating and antitumor effects in humans as well as in animals. In the present study Active Hexose Correlated Compound (AHCC), an extract… Expand
Effect of active hexose correlated compound on the production of nitric oxide in hepatocytes.
- Kosuke Matsui, Y. Kawaguchi, +9 authors T. Okumura
- JPEN. Journal of parenteral and enteral nutrition
- 1 September 2007
BACKGROUND Active hexose correlated compound (AHCC) is a "complex compound" containing polysaccharides. AHCC has been reported to improve the prognosis of postoperative hepatocellular carcinoma… Expand
Protective Effects of Active Hexose Correlated Compound (AHCC) on the Onset of Diabetes Induced by Streptozotocin in the Rat
- K. Wakame
- 1 June 1999
Effects of Active Hexose Correlated Compound (AHCC) on the onset of diabetes were studied in rats treated with streptozotocin (STZ). AHCC was given to male rats at 4% in drinking water. A single i.Y.… Expand
Oligonol a low molecular weight polyphenol of lychee fruit extract inhibits proliferation of influenza virus by blocking reactive oxygen species-dependent ERK phosphorylation.
- Leila Gangehei, M. Ali, W. Zhang, Zhenping Chen, K. Wakame, M. Haidari
- Biology, Medicine
- Phytomedicine : international journal of…
- 1 November 2010
The emergence of resistance to anti-influenza drugs calls for the search for new antiviral molecules with different resistance profiles. Polyphenolic compounds are found in various plants and have… Expand
Evaluation of active hexose correlated compound hepatic metabolism and potential for drug interactions with chemotherapy agents.
- C. M. Mach, Hajime Fugii, K. Wakame, J. Smith
- Journal of the Society for Integrative Oncology
Active hexose correlated compound (AHCC), a Basidiomycotina extract, is a well-tolerated nutritional supplement with no reported adverse effects. It has demonstrated potential antitumor activity and… Expand
Toxicological assessment of enzyme-treated asparagus extract in rat acute and subchronic oral toxicity studies and genotoxicity tests.
- Tomohiro Ito, Tomoko Ono, +5 authors T. Maeda
- Regulatory toxicology and pharmacology : RTP
- 1 March 2014
The safety of enzyme-treated asparagus extract (ETAS) developed as a novel anti-stress functional material was assessed in acute and subchronic studies and genotoxicity assays. In the acute oral dose… Expand
Basic and Clinical Studies on Active Hexose Correlated Comp