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DNA base flipping by a base pair-mimic nucleoside
The structural and thermodynamic analyses suggest that the aromatic hydrocarbon group of X and Z intercalates into a double helix, resulting in the opposite nucleotide base flipping into an unstacked position regardless of the nucleotide species. Expand
Site-selective RNA cleavage by DNA bearing a base pair-mimic nucleoside.
The site-specific RNA hydrolysis suggests that the DNA strand bearing X has the advantage of the site-selective base flipping in the target sequence and the development of a "universal deoxyribozyme" to exclusively cleave a target RNA sequence. Expand
Dynamics and energetics of the base flipping conformation studied with base pair-mimic nucleosides.
To investigate the dynamics and energetics of this unusual conformation in a double helix, base flipping induced by the base pair analogues of deoxyadenosine and deoxycytidine derivatives tethering a phenyl or naphthyl group was investigated. Expand
Control of stereochemical structures of silicon-containing polymeric systems†
Various optically active silicon compounds have been synthesized or separated, and used to synthesize silicon-containing polymers with well-controlled stereochemical structures. Hydrosilylation,Expand
Anionic ring-opening polymerization of optically pure 1 -methyl -1-(1 -naphthyl ) -2,3 -benzosilacyclobut-2 -ene
Polymerization of 1-methyl-1-(1-naphthyl)-2,3-benzosilacyclobut-2-ene as a monomer by n-butyllithium and diphenylmethylsilyllithium gave polymers with reasonably well controlled molecular weight.Expand
Stacking interaction in the middle and at the end of a DNA helix studied with non-natural nucleotides.
The thermal stability of DNA duplexes containing a non-natural nucleotide tethered to a simple aromatic hydrocarbon group devoid of dipole moments and hydrogen bonding sites was measured to understand nucleic acid interactions and to design new non- natural nucleotides. Expand
Synthesis of stereoregular and optically active poly[{methyl(1-naphthyl)silylene}(o-phenylene)methylene] by platinum-catalyzed ring-opening polymerization
Reaction of 1-methyl-1-(1-naphthyl)-2,3-benzosilacyclobut-2-ene (1) with platinum 1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex (PDT) as catalyst (0.1 mol %) gave a polymer, possibly cyclic, withExpand
Induced Circular Dichroism to Optically Active Poly{[methyl(1‐naphthyl)silylene](o‐phenylene)methylene}s Assisted by Supramolecular Complexation with β‐Cyclodextrin
Optically active poly{methyl(1-naphthyl)silylene](o-phenylene)methylene}s with different molecular weights and configurations were prepared, and their supramolecular complexes with β-cyclodextrinExpand