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Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47
The AAA ATPase p97/VCP is involved in many cellular events including ubiquitin‐dependent processes and membrane fusion. In the latter, the p97 adaptor protein p47 is of central importance. In orderExpand
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VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo
NSF and p97 are ATPases required for the heterotypic fusion of transport vesicles with their target membranes and the homotypic fusion of organelles. NSF uses ATP hydrolysis to dissociateExpand
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The localization and phosphorylation of p47 are important for Golgi disassembly–assembly during the cell cycle
In mammalian cells, the Golgi apparatus is disassembled at the onset of mitosis and reassembled at the end of mitosis. This disassembly–reassembly is generally believed to be essential for the equalExpand
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Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97
p47 is a major adaptor molecule of the cytosolic AAA ATPase p97. The principal role of the p97–p47 complex is in regulation of membrane fusion events. Mono‐ubiquitin recognition by p47 has also beenExpand
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VCIP135 deubiquitinase and its binding protein, WAC, in p97ATPase‐mediated membrane fusion
Two distinct p97 membrane fusion pathways are required for Golgi biogenesis: the p97/p47 and p97/p37 pathways. VCIP135 is necessary for both pathways, while its deubiquitinating activity is requiredExpand
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Novel Annelation Method to Pyridine and Isoquinoline by Photochemical Means
Intramolecular photoaddition reactions of 2-(ω-alkenyl)isoquinolin-1(2H)-ones and 1-(ω-alkenyl)pyridin-2(1H)-ones were examined, and the regioselectivity and dependence of these reactions on theExpand
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Cell cycle dependency of rice α‐amylase production in a recombinant yeast
The cell cycle dependency of rice α-amylase production in Saccharomyces cerevisiae was investigated using synchronous and arrested cultures. The results of two separate synchronous cultures, usingExpand
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