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Impact of the advances in age on the gastrointestinal microflora of beagle dogs.
TLDR
The result of this study shows that the advances in age of beagle dogs yield some changes in the microbial population of large bowel in the animals. Expand
Age-related changes in cholesterol and bile acid metabolism in rats.
TLDR
Serum and liver lipid levels increased with age in both strains but the liver phospholipid level remained unchanged, and the proportion of serum alpha-lipoprotein increases and that of beta- and prebeta- lipoproteins slightly decreased. Expand
Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.
TLDR
Diosgenin and beta-sitosterol were administered to CRJ:CD-1 male mice for 15 days, in order to examine the changes in bile acid metabolism, and both phytosterols caused no statistically significant changes in body weight gain and cholesterol absorption. Expand
Cholesterol gallstones in alloxan-diabetic mice.
TLDR
Cholesterol gallstones developed in alloxan-diabetic mice fed excess cholesterol, due to the hyperphagia and the enhancement of cholesterol absorption caused by increases in the synthesis and secretion of cholic acid. Expand
Deoxycholic acid formation in gnotobiotic mice associated with human intestinal bacteria
TLDR
The results indicate that the predominant bacteria, mainly Bacteroides, in human feces comprise one of the main bacterial groups for the deconjugation of bile acid, and clostridia may play an important role in 7α-dehydroxylation of free-form primary bile acids in the intestine although these strains are not predominant. Expand
Bile acid metabolism in partially hepatectomized rats
TLDR
The regenerating liver secretes more bile, bile acids and phospholipids, and less cholesterol than the normal liver, and cholic acid predominates in the bile acid. Expand
Deconjugation of bile acids by human intestinal bacteria implanted in germ-free rats
TLDR
Fecal bile acids in germ-free rats were analyzed after inoculation with Bacteroides vulgatus, Bifidobacterium longum, Escherichia coli or Clostridium ramosum and 7α-Dehydroxylation of bile acid was negligible even after 18 days of inoculation, but a small amount of 7-oxo-bile acid, less than 5%, was formed. Expand
Effect of warfarin on plasma and liver vitamin K levels and vitamin K epoxide reductase activity in relation to plasma clotting factor levels in rats.
TLDR
The results suggest that warfarin inhibits vitamin K epoxide reductase and decreases blood clotting factor synthesis, thus increasing plasma and liver vitamin K1 epoxide levels. Expand
Altered bile acid metabolism in alloxan diabetic rats.
TLDR
It was apparent that synthesis of cholic acid increased while that of chenodeoxycholic acid decreased and the total amount of bile acids synthesized did not change in the diabetic rats. Expand
Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives by Bacteroides intestinalis AM-1 isolated from human feces.
TLDR
In liquid culture, B. intestinalis AM-1 showed a relatively higher productivity of 7-oxo-DCA than Escherichia coli HB101 and Bacteroides fragilis JCM11019(T), which are known to possess 7alpha-HSDH activity. Expand
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