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Cyclooxygenase-1 and -2 in human testicular tumours.
In this study, we investigated the expression of cyclooxygenase (COX)-1 and -2 in human testicular cancer (TC) and normal testis (NT) tissues, as well as the effects of COX ligands on viability andExpand
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High-Density Lipoproteins Protect Endothelial Cells from Tumor Necrosis Factor-α-Induced Apoptosis
High-density lipoproteins (HDL) levels have been shown to be inversely correlated with coronary heart disease, but the mechanisms of the direct protective effect of HDL on endothelial cells are notExpand
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RNA interference targeting SHP‐1 attenuates myocardial infarction in rats
The Src homology domain 2 (SH2)‐containing tyrosine phosphatase‐1 (SHP‐1) plays a key role in apoptosis and decreases phosphorylation of Akt. Apoptosis of cardiomyocytes is thought to contribute toExpand
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Intramuscular Gene Transfer of Soluble Tumor Necrosis Factor-&agr; Receptor 1 Activates Vascular Endothelial Growth Factor Receptor and Accelerates Angiogenesis in a Rat Model of Hindlimb Ischemia
Background—In a pathological setting, tumor necrosis factor (TNF)-&agr; inhibits the proliferative response of endothelial cells through inactivation of receptors for vascular endothelial growthExpand
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High-density lipoproteins protect endothelial cells from tumor necrosis factor-alpha-induced apoptosis.
High-density lipoproteins (HDL) levels have been shown to be inversely correlated with coronary heart disease, but the mechanisms of the direct protective effect of HDL on endothelial cells are notExpand
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Low density lipoproteins develop resistance to oxidative modification due to inhibition of cholesteryl ester transfer protein by a monoclonal antibody.
Although numerous studies have investigated the relationship between cholesteryl ester transfer protein (CETP) and high density lipoprotein (HDL) remodeling, the relationship between CETP and lowExpand
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Nifedipine Prevents Apoptosis of Endothelial Cells Induced By Oxidized Low-density Lipoproteins
Calcium channel blockade has been shown to inhibit experimental atherosclerosis, and early clinical trials suggest that it also reduces atherosclerosis in humans. However, the mechanisms underlyingExpand
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SiRNA targeting SHP-1 accelerates angiogenesis in a rat model of hindlimb ischemia.
Vascular endothelial growth factor (VEGF) receptor-2 (KDR/flk-1) has a tyrosine kinase domain, and once activated, induces the autophosphorylation of the tyrosine residues, which is essential forExpand
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A Protein Tyrosine Phosphatase Inhibitor Accelerates Angiogenesis in a Rat Model of Hindlimb Ischemia
Vascular endothelial growth factor (VEGF) receptor-2 (KDR/flk-1) has a tyrosine kinase domain and, once activated, induces the autophosphorylation of the tyrosine residues. The phosphorylatedExpand
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Calorie restriction increases telomerase activity, enhances autophagy, and improves diastolic dysfunction in diabetic rat hearts
The aims of this study were to investigate the impact of caloric restriction (CR) on cardiac telomere biology in an animal model of diabetes and to examine the signal transduction involved in cellExpand
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