K. Trott

Publications155
h-index38
Citations4,493
Highly Influential Citations114
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Radiation-related heart disease: current knowledge and future prospects.
INTRODUCTIONIt has been recognized since the 1960s that the heart may bedamaged by substantial doses of radiation [>30 Gray (Gy)],such as used to occur during mantle radiotherapy for Hodg-kin… Expand
  • 413
  • 30
Mechanisms of the anti-inflammatory activity of low-dose radiation therapy.
PURPOSE To investigate the hypothesis that modulation of the function of activated macrophages is one of the mechanisms of the clinically observed anti-inflammatory and analgesic efficacy of low-dose… Expand
  • 128
  • 10
The effects of low-dose X-irradiation on the oxidative burst in stimulated macrophages
Purpose : Local irradiation with a dose of around 0.5 Gy is an effective treatment of acute necrotizing inflammations. The hypothesis that low doses of X-rays modulate the oxidative burst in… Expand
  • 78
  • 7
Cell repopulation and overall treatment time.
  • K. Trott
  • Medicine
  • International journal of radiation oncology…
  • 1 October 1990
Prolongation of the overall treatment time in radiotherapy, especially of squamous cell carcinomas of the head and neck, decreases the chances of cure. This is most likely because of the… Expand
  • 111
  • 6
Radiobiological mechanisms of anti-inflammatory radiotherapy.
Radiotherapy with total doses of < or =6 Gy has been given as very effective and low risk treatment of painful degenerative joint diseases and other inflammatory processes. Recent radiobiological… Expand
  • 121
  • 6
Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized…
PURPOSE Accelerated repopulation is a main reason for locoregional failure after fractionated radiotherapy for head and neck squamous cell carcinoma (HNSCC). Epidermal growth factor receptor (EGFR)… Expand
  • 254
  • 5
Therapeutic effects of low radiation doses.
  • K. Trott
  • Medicine
  • Strahlentherapie und Onkologie : Organ der…
  • 1994
PURPOSE This editorial explores the scientific basis of radiotherapy with doses of < 1 Gy for various non-malignant conditions, in particular dose-effect relationships, risk-benefit considerations… Expand
  • 65
  • 5
Delayed lethality, apoptosis and micronucleus formation in human fibroblasts irradiated with X-rays or alpha-particles.
PURPOSE To determine the yields of cell lethality and micronucleus formation measured immediately after irradiation or at delayed times in primary human fibroblasts exposed to X-rays or… Expand
  • 82
  • 4
Persistent increase in the rates of apoptosis and dicentric chromosomes in surviving V79 cells after X-irradiation.
In parallel to delayed reproductive death and delayed micronuclei in surviving V79 cells that have been reported, the frequency of apoptosis and dicentrics was investigated in the same cell line, 1-2… Expand
  • 44
  • 4
Radiation-induced heart disease in rats.
After local irradiation of the rat heart with X ray doses of over 10 Gy (single dose), animals developed symptoms of radiation-induced heart disease, which at higher doses would lead to fatal cardiac… Expand
  • 131
  • 3