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Decreased levels of brain-derived neurotrophic factor in serum of chronic schizophrenic patients
Neurotrophic factors regulate neuronal development as well as synaptic plasticity, and their impairment is often implicated as a cause of schizophrenia. Among various neurotrophic molecules,Expand
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Selective reduction of a PDZ protein, SAP‐97, in the prefrontal cortex of patients with chronic schizophrenia
Many postsynaptic density proteins carrying postsynaptic density‐95/discs large/zone occludens‐1 (PDZ) domain(s) interact with glutamate receptors to control receptor dynamics and synapticExpand
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Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients
Previous neuropathological studies have revealed that the corticolimbic system of schizophrenic patients expresses abnormal levels of various synaptic molecules, which are known to be influenced byExpand
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Abnormal expression of epidermal growth factor and its receptor in the forebrain and serum of schizophrenic patients
Epidermal growth factor (EGF) comprises a structurally related family of proteins containing heparin-binding EGF-like growth factor (HB-EGF) and transforming growth factor alpha (TGFα) that regulatesExpand
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14-3-3 protein eta chain gene (YWHAH) polymorphism and its genetic association with schizophrenia.
Recent genetic analyses have suggested a linkage between schizophrenia and the chromosomal region 22q12-q13. 14-3-3 protein, abundant in the brain, mediates interactions between diverse molecules ofExpand
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A decrease in interleukin-1 receptor antagonist expression in the prefrontal cortex of schizophrenic patients
Interleukin-1 (IL-1) mediates psychological stress responses by regulating monoamine metabolism and secretion of corticotropin-releasing factor, and is therefore, implicated in various psychiatricExpand
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Immunohistochemical Changes of the Transcription Regulatory Factors in Rat Striatum after Methamphetamine Administration
ABSTRACT: We have found evidence for cyclic adenosine monophosphate (cAMP) response element (CRE) in the 5′‐upstream region of the human 14.3.3 η chain gene during studies on isolation and structureExpand
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Expressed emotion from the Five‐Minute Speech Sample and relapse of out‐patients with schizophrenia a
We investigated the relationship between 9‐month relapse of 40 outpatients with schizophrenia and expressed emotion (EE) evaluated by the Five‐Minute Speech Sample (FMSS). The results of this studyExpand
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Isolation and structure of the mouse 14-3-3 η chain gene and the distribution of 14-3-3 η mRNA in the mouse brain
Abstract 14-3-3 protein is a brain-specific protein discovered by Moore and Perez, but at present is thought to be a multifunctional protein. To clarify the brain-specific function of the protein, weExpand
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Effects of exogenous steroids on androgen receptors in fetal guinea pig brain.
We treated pregnant guinea pigs on Day 50 of gestation with 10 mg testosterone propionate (TP), obtaining fetuses 2, 4, 8, or 18 h later as well as after 5 days of treatment. In a second group ofExpand
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