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Endoplasmic reticulum stress as a novel therapeutic target in heart diseases.
The endoplasmic reticulum (ER) is a multifunctional organelle responsible for the synthesis and folding of proteins as well as calcium storage and signaling. Perturbations of ER function cause ERExpand
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Epidemiology of congenital coronary artery anomalies: a coronary arteriography study on a central European population.
The anatomical patterns and frequency of occurrence of congenital coronary anomalies (CCA) in a Central European cohort has not yet been studied. The angiographic data of 7,694 consecutive patientsExpand
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Role of reactive oxygen species and poly-ADP-ribose polymerase in the development of AZT-induced cardiomyopathy in rat.
The short term cardiac side-effects of AZT (3'-azido-3'-deoxythymidine, zidovudine) was studied in rats to understand the biochemical events contributing to the development of AZT-inducedExpand
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Prevention of Doxorubicin-Induced Acute Cardiotoxicity by an Experimental Antioxidant Compound
Doxorubicin is a widely used anticancer agent, but its application is restricted by its cardiotoxic side effects. The current theory of its cardiotoxicity is based on free radical formation. TheExpand
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Improved Flow Cytometric Assessment Reveals Distinct Microvesicle (Cell-Derived Microparticle) Signatures in Joint Diseases
Introduction Microvesicles (MVs), earlier referred to as microparticles, represent a major type of extracellular vesicles currently considered as novel biomarkers in various clinical settings such asExpand
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Effects of Moderate Aerobic Exercise Training on Hemorheological and Laboratory Parameters in Ischemic Heart Disease Patients
Background and Design In this study we set out to determine the effects of long-term physical training on hemorheological, laboratory parameters, exercise tolerability, psychological factors inExpand
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Akt activation induced by an antioxidant compound during ischemia-reperfusion.
Molecular mechanisms of cardioprotection afforded by modified mexiletine compounds were investigated during ischemia-reperfusion (IR) in Langendorff perfused hearts. Rat hearts were subjected to aExpand
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Physiological indicators of fluoride exposure and utilization: an epidemiological study.
Individual samples of urine, fingernails, head-hair, saliva, plaque and enamel were collected from three groups of Hungarian children, aged 14 years, who were exposed to contrasting water fluorideExpand
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Deformability analysis of sickle blood using ektacytometry.
Sickle cell disease (SCD) is characterized by decreased erythrocyte deformability, microvessel occlusion and severe painful infarctions of different organs. Ektacytometry of SCD red blood cells (RBC)Expand
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Clinical importance of aspirin and clopidogrel resistance.
Aspirin and clopidogrel are important components of medical therapy for patients with acute coronary syndromes, for those who received coronary artery stents and in the secondary prevention ofExpand
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