• Publications
  • Influence
Periodic synchronized bursting and intracellular calcium transients elicited by low magnesium in cultured cortical neurons.
1. In Mg(2+)-free external solution, rat cortical neurons in cultured networks entered a stable firing mode, consisting of regular bursts of action potentials superimposed on long-lastingExpand
  • 227
  • 17
A system for MEA-based multisite stimulation
A MEA-based multisite stimulation and recording system with novel interface circuit modules, in which preamplifiers and transistor transistor logic-driven solid-state switching devices are integrated. Expand
  • 189
  • 7
Ion conducting polymer microelectrodes for interfacing with neural networks
We have examined the stimulation and recording properties of conjugated polymer microelectrode arrays as interfaces with neural networks of dissociated cortical cells. In particular the stimulationExpand
  • 101
  • 5
Direct Observation of ATP-Induced Conformational Changes in Single P2X4 Receptors
The ATP-gated P2X4 receptor is a cation channel, which is important in various pathophysiological events. The architecture of the P2X4 receptor in the activated state and how to change its structureExpand
  • 94
  • 3
  • PDF
Conductive Polymer Combined Silk Fiber Bundle for Bioelectrical Signal Recording
Electrode materials for recording biomedical signals, such as electrocardiography (ECG), electroencephalography (EEG) and evoked potentials data, are expected to be soft, hydrophilic andExpand
  • 101
  • 3
  • PDF
Small-Volume On-Line Sensor for Continuous Measurement of γ-Aminobutyric Acid
We report the first on-line electrochemical sensor for the continuous measurement of γ-aminobutyric acid (GABA), which is a well-known inhibitory neurotransmitter in the nervous system. The sensor isExpand
  • 55
  • 2
Highly conductive stretchable and biocompatible electrode-hydrogel hybrids for advanced tissue engineering.
Hydrogel-based, molecular permeable electronic devices are considered to be promising for electrical stimulation and recording of living tissues, either in vivo or in vitro. This study reports theExpand
  • 102
  • 2
Improvement in signal reliability when measuring l-glutamate released from cultured cells using multi-channel microfabricated sensors
Abstract We used a micromachining technique to fabricate a very reliable amperometric glutamate sensor consisting of dual channel thin layer flow cells for the highly selective measurement ofExpand
  • 22
  • 2
Periodic bursting of cultured cortical neurons in low magnesium: cellular and network mechanisms.
The origin of the 0.1 Hz bursting of cultured rat cortical neurons in zero Mg2+ was studied by whole-cell recording, fluo-3 Ca2+ imaging, and multi-unit electrode array recording. A model is proposedExpand
  • 13
  • 2
Vapor–liquid–solid growth of vertically aligned InP nanowires by metalorganic vapor phase epitaxy
Abstract In this study, a detailed investigation of the growth of vertically oriented and surface mounted InP nanowires has been carried out. They were grown by metal organic vapor phase epitaxy onExpand
  • 48
  • 2