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Connective tissue content and myocardial stiffness in pressure overload hypertrophy A combined study of morphologic, morphometric, biochemical, and mechanical parameters
SummaryWe investigated samples of left ventricular myocardium from Goldblatt II (4 and 8 weeks after operation) and spontaneously hypertensive rats (SHR; 40 and 80 weeks old) by histological andExpand
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Hypertrophy due to chronic volume overloading in the dog heart. A morphometric study
SummaryCardiac hypertrophy due to chronic volume overloading was produced in dogs by experimental complete AV-block. Ten weeks after operation a quantitative electron microscopic study was carriedExpand
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The ulstrastructure of sarcomeres in hypertrophied canine myocardium in spontaneous subaortic stenosis
SummaryUltrastructural alterations of sarcomeric structure were found in canine congenital subaortic stenosis leading to cardiac hypertrophy.These changes consisted of plaque-like accumulation ofExpand
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High-energy phosphates, myocardial contractile function and material properties after short periods of oxygen deficiency
SummaryTo investigate myocardial performance and diastolic properties after repeated periods of oxygen deficiency auxotonic and isovolumic measurements were performed after three periods (4 min) ofExpand
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Nuclei in testicular feminization (Tfm) are not activated by intact testosterone receptor complexes: A morphometric study in striated urethral muscle of mosaic mice
SummarySex reversed mice heterozygous for the X-linked Tfm mutation are mosaics with respect to the Tfm locus. In the androgen-dependent striated urethral muscle, nuclei coding for the intactExpand
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Left Ventricular Hypertrophy
Long-lasting cardiac overload in man as well as in experimental animals leads to an increase in heart weight (or better: heart weight/body weight ratio). Cardiac hypertrophy can result from increasedExpand
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Intact testosterone receptor complex does not induce RNA synthesis of tfm-nuclei in multinucleated urethral muscle fibres of mosaic mice
SummaryThe X-linked testicular feminization mutation (Tfm) of the mouse leads to androgen insensitivity of target cells. Through the autosomal sex reversed (Sxr) factor we have converted femaleExpand
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