• Publications
  • Influence
Reconstructing Indian Population History
TLDR
It is predicted that there will be an excess of recessive diseases in India, which should be possible to screen and map genetically and is higher in traditionally upper caste and Indo-European speakers. Expand
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
TLDR
It is demonstrated that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans. Expand
Ancient human genomes suggest three ancestral populations for present-day Europeans
TLDR
It is shown that the great majority of present-day Europeans derive from at least three highly differentiated populations: West European Hunter-Gatherers (WHG), who contributed ancestry to all Europeans but not to Near Easterners; Ancient North Eurasians (ANE); and Early European Farmers (EEF), who were mainly of Near Eastern origin but also harbored WHG-related ancestry. Expand
Reconstructing the Origin of Andaman Islanders
TLDR
Analysis of complete mitochondrial DNA sequences from Onges and Great Andaman populations revealed two deeply branching clades that share their most recent common ancestor in founder haplogroup M, with lineages spread among India, Africa, East Asia, New Guinea, and Australia. Expand
Genetic evidence for recent population mixture in India.
Most Indian groups descend from a mixture of two genetically divergent populations: Ancestral North Indians (ANI) related to Central Asians, Middle Easterners, Caucasians, and Europeans; andExpand
Phylogeography and origin of Indian domestic goats.
TLDR
The present investigation of 363 goats belonging to 10 different breeds from different geographic regions of India using mtDNA sequence data from the HVRI region finds evidence for population structure and novel lineages in Indian goats and proposes a more complex origin for domestic goats. Expand
Ancient human genomes suggest three ancestral populations for present-day Europeans
TLDR
It is shown that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians; and early European farmers, who were mainly of Near Eastern origin but also harboured west Europeanhunter-gatherer related ancestry. Expand
Genetic Affinities of the Andaman Islanders, a Vanishing Human Population
TLDR
The data indicate that the Andamanese have closer affinities to Asian than to African populations and suggest that they are the descendants of the early Palaeolithic colonizers of Southeast Asia. Expand
In situ origin of deep rooting lineages of mitochondrial Macrohaplogroup 'M' in India
TLDR
The result indicates that the Indian mtDNA pool consists of several deep rooting lineages of macrohaplogroup 'M' suggesting in-situ origin of these haplogroups in South Asia, most likely in the India. Expand
Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin
TLDR
It is demonstrated that UCP2 over-expression leads to development of tumors in vivo in an orthotopic model of breast cancer, and genipin suppresses the tumor promoting function of U CP2. Expand
...
1
2
3
4
5
...