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Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer
TLDR
In univariate survival analysis, intensity of CA IX expression was a predictor of DFS and DSS, both being markedly longer in tumours with negative or weakly positive staining.
Zaspopathy in a large classic late-onset distal myopathy family.
TLDR
The disorder in one of the well-characterized autosomal dominant distal myopathy families, the Markesbery et al. family, is caused by ZASP mutation A165V, and haplotype studies in this family and in five other unrelated families with European ancestry share common markers at the locus suggesting the existence of a founder mutation.
Cloning of a novel phospholipase A2 from the cnidarian Adamsia carciniopados.
Securin promotes the identification of favourable outcome in invasive breast cancer
TLDR
Securin could be useful in clinical pathology to intensify the power of the established prognosticators of invasive breast cancer and, especially, to assist in identifying patients with a more favourable outcome than that indicated by Ki-67 alone.
FHOD1, a Formin Upregulated in Epithelial-Mesenchymal Transition, Participates in Cancer Cell Migration and Invasion
TLDR
It is shown that FHOD1 upregulation occurs during cancer cell EMT in vivo, which indicates that FhOD1 may contribute to tumour progression, and cytoskeletal changes in EMT are participated in.
Tumor-infiltrating lymphocytes and CD8+ T cells predict survival of triple-negative breast cancer
Tumor inflammatory response was evaluated as a prognostic feature in triple-negative breast cancer (TNBC) and compared with the clinical prognosticators of breast cancer and selected biomarkers of
mRNA differential display of gene expression in colonic carcinoma
TLDR
Fluorescent mRNA differential display can be applied to the identification of novel cancer‐related genes for diagnostic, prognostic and therapeutic purposes.
Biochemical and clinical approaches in evaluating the prognosis of colon cancer.
TLDR
Tumour stage is superior in estimating the prognosis of patients with colonic cancer compared with the grading of cell cycle regulators or histological grade of the cancer.
Characterization of Diaphanous-related formin FMNL2 in human tissues
TLDR
Immunohistochemical analysis of 26 different human tissues showed that FMNL2 is widely expressed, in agreement with the mRNA profile, and the expression is especially strong in gastrointestinal and mammary epithelia, lymphatic tissues, placenta, and in the reproductive tract.
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