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Cytotoxic flavonoids from Vitex agnus-castus.
Structures and cytotoxic activity relationship of casearins, new clerodane diterpenes from Casearia sylvestris Sw.
Casearins G-R, new cytotoxic clerodane diterpenes have been isolated from the leaves of Casearia sylvestris Sw. (Flacourtiaceae). Their structures have been elucidated by spectroscopic methods and…
Cytotoxic diterpenes from the rhizomes of Hedychium coronarium.
Cytotoxic aromatic triterpenes from Maytenus ilicifolia and Maytenus chuchuhuasca.
The isolation and structure elucidation of four cytotoxic aromatic triterpenes [1-4] along with three known quinoid triterpenes [5-7] from the South American medicinal plants Maytenus ilicifolia and…
Conformational behavior of oxygenated mycobacterial mycolic acids from Mycobacterium bovis BCG.
Anthraquinones, naphthohydroquinones and naphthohydroquinone dimers from Rubia cordifolia and their cytotoxic activity.
- H. Itokawa, Z. Ibraheim, Y. Qiao, K. Takeya
- ChemistryChemical & pharmaceutical bulletin
- 15 October 1993
Further investigation of the roots of Rubia cordifolia resulted in the isolation of four new naphthohydroquinones and two naphthaquinone dimers and the structures of these compounds were established by various chemical and spectroscopic methods including two dimensional NMR techniques.
Antitumor principles from Ginkgo biloba L.
- H. Itokawa, N. Totsuka, K. Nakahara, K. Takeya, J. Lepoittevin, Y. Asakawa
- Chemistry, BiologyChemical & pharmaceutical bulletin
- 25 July 1987
Seven long-chain phenols were isolated from Ginkgo biloba L. Three of them, anacardic acid (Ib), bilobol (IIa), and cardanol (IIIa), showed antitumor activity against Sarcoma 180 ascites in mice. The…
Diarylheptanoids from the Rhizomes of Curcuma xanthorrhiza and Alpinia officinarum
Five diarylheptanoids including two new compounds were isolated from the rhizomes of Curcuma xanthorrhiza (Zingiberaceae). The structures of the new compounds were determined to be octahydrocurcumin…
Cytotoxic quassinoids from Simaba cedron.
- A. Ozeki, Y. Hitotsuyanagi, E. Hashimoto, H. Itokawa, K. Takeya, S. de Mello Alves
- ChemistryJournal of natural products
- 5 May 1998
Four new quassinoids, cedronolactones A-D (1-4), together with nine known compounds, simalikalactone D (5), chaparrinone (6), chaparrin (7), glaucarubolone (8), glaucarubol (9), samaderine Z (10),…
Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria.
- K. Osawa, H. Yasuda, T. Maruyama, H. Morita, K. Takeya, H. Itokawa
- Chemistry, MedicineChemical & pharmaceutical bulletin
- 25 November 1992
The methanolic extract of Swartzia polyphylla DC had antibacterial activity against cariogenic bacteria, the mutans Streptococci, and this effect was not detected on isoflavone derivatives.