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Expression and characterization of Rab38, a new member of the Rab small G protein family
Abstract Rab38 is a new member of the Rab small G protein family that regulates intracellular vesicle trafficking. Rab38 is expressed in melanocytes and it has been clarified that a point mutation in… Expand
[A case of chronic thyroiditis associated with vasculitic neuropathy].
Syntheses and antitumor activities of D- and L-2'-deoxy-4'-thio pyrimidine nucleosides
Abstract Both enantiomers of 2′-deoxy-4′-thiouridine (9) and 15, 4′-thiothymidine (10) and 16, and 2′-deoxy-4′-thiocytidine (14) and 17 and… Expand
Effects of interleukin‐1β on DNA synthesis in rat alveolar type II cells in primary culture
Proliferation of alveolar type II cells is critical for restoration of the integrity of alveolar epithelium in alveolar injuries caused by a number of different aetiologies. Because effects of… Expand
[A quantitative study on the intermediolateral cells of the thoracic cord in degenerative diseases of the nervous system (author's transl)].
Beta1-adrenoceptor stimulation by high-dose terbutaline downregulates terbutaline-stimulated alveolar fluid clearance in ex vivo rat lung.
: Because high-dose terbutaline and isoproterenol (10(-3) M), beta2-adrenergic agonists, failed to increase alveolar fluid clearance, the mechanisms responsible for this effect were examined in ex… Expand
[Temporal arteritis associated with polyneuritis and polymyalgia rheumatica (author's transl)].
Asymmetric synthesis of D- and L-2-deoxy-4-thioriboscs
Abstract Both D- and L-enantiomers of 2-deoxy-4-thioribose derivatives 12 and 17 were prepared stereospecifically in 12 steps from 1,3-propanediol. The key intermediary 2,3-epoxy alcohols, 8 and 15… Expand
A new process for synthesis of the astrocyte activation suppressor, ONO-2506
Development of a new process for the synthesis of ONO-2506, an agent that suppresses astrocyte activation, is described. Previous processes that involved asymmetric synthesis with a chiral auxiliary… Expand
[Demyelinating encephalitis associated with progressive systemic scleroderma].