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Guidelines for the Treatment of Acidaemia with THAM
SummaryTHAM (trometamol; tris-hydroxymethyl aminomethane) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. At 37°C, the pK (the pHExpand
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Physiological and Pharmacological Interactions of Marihuana (THC) with Drugs and Anesthetics
THC is one of the 60 natural cannabinoids contained in the marihuana plant, which is psychoactive. It is a long-acting agent with multiple pharmacological effects. THC produces bronchodilation, butExpand
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Psychoactive cannabinoids and membrane signaling
THC‐like psychoactive cannabinoids permeate the lipid bilayer of the membrane, altering its physicochemical properties and activating phospholipases. As a result, an increased production ofExpand
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A molecular basis of the therapeutic and psychoactive properties of cannabis (Δ9-tetrahydrocannabinol)
All of the therapeutic properties of marihuana (analgesic, antiemetic, appetite stimulant, antiglaucoma) have been duplicated by the tetrahydrocannabinol (THC) molecule or its synthetic derivatives.Expand
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Receptor and Nonreceptor Membrane-Mediated Effects of THC and Cannabinoids
A strict chemical nomenclature is first proposed. It is based on the definitions of cannabinoids, psychoactive (THC) and nonpsychoactive (CBD, CBN, and THC-11 oic acid), and of identified receptorsExpand
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Cannabinoids in the Treatment of Pain
The mechanisms of the analgesic properties of marihuana and cannabinoids anecdotally reported until this day have never been clearly defined in pharmacology or in clinical medicine. The purpose ofExpand
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Pharmacokinetic Profile of Morphine in Parturients Following Intravenous or Epidural Administration
Background and Objectives. Study of the pharmacokinetic profile of morphine following intravenous or epidural administration in parturients undergoing elective cesarean delivery. Methods. SixteenExpand
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The Medical Use of Marihuana and THC in Perspective
The curative properties attributed to marihuana for several thousand years have proved to be disappointing. The ancient oriental claims of marihuana as a pain soother and for the relief of muscleExpand
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