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GABA-cAMP Response Element-Binding Protein Signaling Regulates Maturation and Survival of Newly Generated Neurons in the Adult Hippocampus
TLDR
Results indicate that CREB signaling is a central pathway in adult hippocampal neurogenesis, regulating the development and survival of new hippocampal neurons downstream of GABA-mediated excitation. Expand
Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis
Ruth Beckervordersandforth,* Birgit Ebert, Iris Sch€ affner, Jonathan Moss, Christian Fiebig, Jaehoon Shin, Darcie L. Moore, Laboni Ghosh, Mariela F. Trinchero, Carola Stockburger, KristinaExpand
Mitochondria Modify Exercise-Induced Development of Stem Cell-Derived Neurons in the Adult Brain
TLDR
It is shown that the development of new neurons from stem cells in adult mice is paralleled by extensive changes to mitochondrial mass, distribution, and shape, which indicates that adult hippocampal neurogenesis requires adaptation of the mitochondrial compartment and suggests that mitochondria are targets for enhancing neurogenes-dependent hippocampal plasticity. Expand
Deep Brain Stimulation for Essential Tremor: Targeting the Dentato‐Rubro‐Thalamic Tract?
The aim of our study was to evaluate the influence of the stimulation site relative to the dentato‐rubro‐thalamic tract (DRTT) on the alleviation of tremor in deep brain stimulation.
Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis
TLDR
It is shown that the adult hippocampal neurogenic lineage is critically dependent on the mitochondrial electron transport chain and oxidative phosphorylation machinery at the stage of the fast proliferating intermediate progenitor cell. Expand
The variability of atlas-based targets in relation to surrounding major fibre tracts in thalamic deep brain stimulation
TLDR
A considerable variability is found of the location of atlas-based target points of the ventralis intermedius nucleus in relation to neighbouring major fibre tracts in individual patients, suggesting that individualised targeting to structures not directly visible on conventional MRI is necessary. Expand
DTI-based deterministic fibre tracking of the medial forebrain bundle
TLDR
Deterministic fibre tracking with standardised ROIs provides constant and reproducible delineations of the medial forebrain bundle that might help to adjust targeting in DBS for psychiatric disorders. Expand
Probabilistic vs. deterministic fiber tracking and the influence of different seed regions to delineate cerebellar‐thalamic fibers in deep brain stimulation
TLDR
Compared tractography approaches for identifying cerebellar‐thalamic fiber bundles relevant to planning target sites for deep brain stimulation (DBS) suggest that probabilistic tracking is more sensitive and robust in detecting the DRTT but harder to implement than deterministic approaches. Expand
Epidemiology and vectors of Dracunculus medinensis in northwest Burkina Faso, West Africa.
  • K. Steib, P. Mayer
  • Geography, Medicine
  • Annals of tropical medicine and parasitology
  • 1 April 1988
TLDR
The use of protective water filters proved to be the only adequate method for guinea worm control in the project area and cyclopoid species were found for the first time acting as natural intermediate hosts of D. medinensis. Expand
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