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White matter microstructure alterations of the medial forebrain bundle in melancholic depression.
BACKGROUND The medial forebrain bundle (MFB) is a key structure of the reward system and connects the ventral tegmental area (VTA) with the nucleus accumbens (NAcc), the medial and lateralExpand
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Resting-State Hyperperfusion of the Supplementary Motor Area in Catatonia
Abstract Catatonia is a psychomotor syndrome that not only frequently occurs in the context of schizophrenia but also in other conditions. The neural correlates of catatonia remain unclear due toExpand
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Deficient supplementary motor area at rest: Neural basis of limb kinetic deficits in Parkinson's disease
Parkinson's disease (PD) patients frequently suffer from limb kinetic apraxia (LKA) affecting quality of life. LKA denotes an impairment of precise and independent finger movements beyondExpand
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Aberrant Hyperconnectivity in the Motor System at Rest Is Linked to Motor Abnormalities in Schizophrenia Spectrum Disorders
Motor abnormalities are frequently observed in schizophrenia and structural alterations of the motor system have been reported. The association of aberrant motor network function, however, has notExpand
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Ventral striatum gray matter density reduction in patients with schizophrenia and psychotic emotional dysregulation☆
Introduction Substantial heterogeneity remains across studies investigating changes in gray matter in schizophrenia. Differences in methodology, heterogeneous symptom patterns and symptomExpand
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Gesture Performance in Schizophrenia Predicts Functional Outcome After 6 Months
The functional outcome of schizophrenia is heterogeneous and markers of the course are missing. Functional outcome is associated with social cognition and negative symptoms. Gesture performance andExpand
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Cerebral white matter structure is associated with DSM-5 schizophrenia symptom dimensions
Diffusion tensor imaging (DTI) studies have provided evidence of widespread white matter (WM) abnormalities in schizophrenia. Although these abnormalities appear clinically significant, theExpand
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Physical Activity in Schizophrenia is Higher in the First Episode than in Subsequent Ones
Schizophrenia is frequently associated with abnormal motor behavior, particularly hypokinesia. The course of the illness tends to deteriorate in the first years. We aimed to assess gross motorExpand
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Structural brain correlates of defective gesture performance in schizophrenia
INTRODUCTION The neural correlates of impaired performance of gestures are currently unclear. Lesion studies showed variable involvement of the ventro-dorsal stream particularly left inferior frontalExpand
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Tardive Dyskinesia Associated with Atypical Antipsychotics: Prevalence, Mechanisms and Management Strategies
All antipsychotics, including the atypical antipsychotics (AAPs), may cause tardive dyskinesia (TD), a potentially irreversible movement disorder, the pathophysiology of which is currently unknown.Expand
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