Alterations in brain aldehyde dehydrogenase activity modify ethanol-induced conditioned taste aversion.
It is suggested that brain ALDH may play a role in the mediation of ethanol-induced conditioned taste aversion and it is conceivable that ALDH plays this role by regulating the levels of acetaldehyde in brain.
Superior outcome of females over males after brief treatment for the reduction of heavy drinking.
- M. Sanchez-Craig, G. Leigh, K. Spivak, H. Lei
- MedicineBritish Journal of Addiction
- 1 April 1989
Females were more successful than males in all conditions and mean changes in GGT and MCV levels lended support to the change in drinking status (from heavy drinker at intake to moderate drinkers at follow-up), based on clients' self-reports.
Alterations in brain aldehyde dehydrogenase activity modify the locomotor effects produced by ethanol in rats.
It is suggested that brain ALDH may play a role in the mediation of locomotor effects produced by ethanol because it is conceivable that ALDH plays this role by regulating the levels of acetaldehyde in brain.
Effects of 3-amino-1,2,4-triazole on ethanol-induced open-field activity: evidence for brain catalase mediation of ethanol's effects.
The results of the present study suggest that brain catalase activity may be involved in ethanol's effects and provide further support for the notion that acetaldehyde may be produced directly in the brain viaCatalase and that it may be a factor mediating some of ethanol's central effects.
Superior outcome of females over males after brief treatment for the reduction of heavy drinking: replication and report of therapist effects.
- M. Sanchez-Craig, K. Spivak, R. Davila
- PsychologyBritish Journal of Addiction
- 1 July 1991
In this study the more experienced therapists had significantly lower rates of client dropout than the less experienced, and changes from baseline in GGT, MCV, and the Digit Symbol Test corroborated the clients' reports of drinking.
Assisting problem drinkers to change on their own: effect of specific and non-specific advice.
- K. Spivak, M. Sanchez-Craig, R. Davila
- MedicineAddiction
- 1 September 1994
It was concluded that drinkers intending to cut down on their own derive greater benefit from materials containing specific instructions to develop moderate drinking than from those providing general information on alcohol effects.
...
...