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Replacement of the anterior cruciate ligament by an allogeneic tendon graft. An experimental study in the dog.
TLDR
The revascularisation and remodelling of allografts used to replace the anterior cruciate ligament in the canine knee were studied by microangiographic, histological and biomechanical methods and showed no evidence of immunological rejection.
Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells.
TLDR
Implantation of a TEC into chondral defects initiated repair with a chondrogenic-like tissue, as well as secure biological integration to the adjacent cartilage, which revealed mechanical properties similar to those of normal porcine cartilage in static compression and friction tests.
Single- versus bi-socket anterior cruciate ligament reconstruction using autogenous multiple-stranded hamstring tendons with endoButton femoral fixation: A prospective study.
TLDR
Both single- and bi-socket ACL reconstruction using autogenous multiple-stranded hamstring tendons with EndoButton fixation provided satisfactory anterior stability, and there were no statistically significant differences in subjective results or measured restored stability between the 2 groups.
Decorin antisense gene therapy improves functional healing of early rabbit ligament scar with enhanced collagen fibrillogenesis in vivo
TLDR
The first report that in vivo manipulation of collagen fibrillogenesis improves tissue function during repair processes with gene therapy is reported, suggesting the potential use of this type of approach to improve the healing of various soft tissues to better understand specific structure‐function relationships in scars.
Human Meniscus Cell: Characterization of the Primary Culture and Use for Tissue Engineering
TLDR
The finding that cells collected from small surgical specimens of human meniscs could be cultured, propagated, and seeded onto a collagen scaffold holds promise for the development of a cell-based, tissue engineered collagen meniscus.
Maturation of allograft tendons transplanted into the knee. An arthroscopic and histological study.
TLDR
It is suggested that the grafts reach maturity within the first 18 months and remain unchanged as viable ligaments thereafter.
Subluxation of the patella. Computed tomography analysis of patellofemoral congruence.
TLDR
It is indicated that patellar subluxation can be detected more accurately by using computed tomography with the knee in full extension than by using conventional axial roentgenograms.
Conservative treatment of isolated injuries to the posterior cruciate ligament in athletes.
TLDR
Knees with an isolated injury to the PCL with concomitant articular damage may be successfully managed by conservative treatment, and most remained athletically active.
In vitro generation of a scaffold-free tissue-engineered construct (TEC) derived from human synovial mesenchymal stem cells: biological and mechanical properties and further chondrogenic potential.
TLDR
The basic TEC generates with human synovial mesenchymal stem cells possesses sufficiently self-supporting mechanical properties in spite of not containing artificial scaffolding and may be a promising method to promote cartilage repair for future clinical application.
Quantitative evaluation after arthroscopic anterior cruciate ligament reconstruction
TLDR
It is concluded that the allograft procedure is advantageous over the patellar tendon autograft in terms of better restoration of anterior stability.
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