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Carrier-mediated processes in blood–brain barrier penetration and neural uptake of paraquat
Due to the structural similarity to N-methyl-4-phenyl pyridinium (MPP(+)), paraquat might induce dopaminergic toxicity in the brain. However, its blood--brain barrier (BBB) penetration has not beenExpand
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Targeting mitochondrial ATP-sensitive potassium channels—a novel approach to neuroprotection
Mitochondrial responses to ischemic stress play an important role in necrosis and apoptosis of brain cells. Recent studies using several different experimental preparations have shown that activationExpand
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MitoKATP opener, diazoxide, reduces neuronal damage after middle cerebral artery occlusion in the rat
We investigated effects of diazoxide, a selective opener of mitochondrial ATP-sensitive K+ (mitoKATP) channels, against brain damage after middle cerebral artery occlusion (MCAO) in male Wistar rat...
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Enhancement of salt tolerance in soybean with NaCl pretreatment
Acclimation response to salt stress in soybean (Glycine max [L.] Merr. cv. Lee) was found in this study. Soybean seedlings were exposed to 0, 34 and 68 mM NaCl for 23 days (pretreatment), thereafterExpand
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Activation of mitochondrial ATP-sensitive potassium channels prevents neuronal cell death after ischemia in neonatal rats
Activation of mitochondrial ATP-sensitive potassium channels (mK(ATP)) has been shown to protect against cell death following ischemia/reperfusion in the heart but not in brain. We examined whetherExpand
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N-methyl-D-aspartate-induced vasodilation is mediated by endothelium-independent nitric oxide release in piglets.
N-methyl-D-aspartate (NMDA) elicits pial arteriolar dilation that has been associated with neuronal nitric oxide (NO) production. However, endothelial factors or glial P-450 epoxygenase products mayExpand
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Opening of Mitochondrial ATP-Sensitive Potassium Channels Is a Trigger of 3-Nitropropionic Acid–Induced Tolerance to Transient Focal Cerebral Ischemia in Rats
Background and Purpose— The role of mitochondrial ATP-sensitive potassium channels (mitoKATP) in ischemic tolerance has been well documented in heart, but little work has been done in brain. ToExpand
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Mechanisms involved in the cerebrovascular dilator effects of cortical spreading depression
Cortical spreading depression (CSD) leads to dramatic changes in cerebral hemodynamics. However, mechanisms involved in promoting and counteracting cerebral vasodilator responses are unclear. Here weExpand
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MitoK(ATP) opener, diazoxide, reduces neuronal damage after middle cerebral artery occlusion in the rat.
We investigated effects of diazoxide, a selective opener of mitochondrial ATP-sensitive K(+) (mitoK(ATP)) channels, against brain damage after middle cerebral artery occlusion (MCAO) in male WistarExpand
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Effects of Non-stomatal Components on Photosynthesis in Soybean under Salt Stress
To elucidate the physiological mechanism of inhibition of photosynthesis by salt stress in soybean (Glycine max (L.) Merr.), the photosynthetic activity, Na+ accumulation and ABA content of twoExpand
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