• Publications
  • Influence
Polymeric systems for controlled drug release.
s, and 360 patents, and edited 12 books. He has also received over 80 major awards including the Gairdner Foundation International Award, Lemelson-MIT prize, ACS’s Applied Polymer Science and PolymerExpand
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Surface plasmon resonance analysis of dynamic biological interactions with biomaterials.
Surface plasmon resonance (SPR) is an optical technique that is widely gaining recognition as a valuable tool to investigate biological interactions. SPR offers real time in situ analysis of dynamicExpand
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Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo
We exploited leukocyte–endothelial cell adhesion chemistry to generate biodegradable particles that exhibit highly selective accumulation on inflamed endothelium in vitro and in vivo.Expand
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The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles.
Stroke causes extensive cellular loss that leads to a disintegration of the afflicted brain tissue. Although transplanted neural stem cells can recover some of the function lost after stroke,Expand
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Mathematical modelling of engineered tissue growth using a multiphase porous flow mixture theory
This paper outlines the framework of a porous flow mixture theory for the mathematical modelling of in vitro tissue growth, and gives an application of this theory to an aspect of tissue engineering.Expand
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The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation.
Regenerating bone tissue involves complex, temporal and coordinated signal cascades of which bone morphogenic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF(165)) play a prominentExpand
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Liver tissue engineering: a role for co-culture systems in modifying hepatocyte function and viability.
A major limitation in the construction of a functional engineered liver is the short-term survival and rapid de-differentiation of hepatocytes in culture. Heterotypic cell-cell interactions may haveExpand
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Tissue engineering: strategies, stem cells and scaffolds
Tissue engineering scaffolds are designed to influence the physical, chemical and biological environment surrounding a cell population. In this review we focus on our own work and introduce a rangeExpand
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Dental pulp stem cells: function, isolation and applications in regenerative medicine
Dental pulp stem cells (DPSCs) are a promising source of cells for numerous and varied regenerative medicine applications. Their natural function in the production of odontoblasts to createExpand
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Long-term culture of functional liver tissue: three-dimensional coculture of primary hepatocytes and stellate cells.
One of the greatest challenges in the attempt to create functional liver tissue in vitro is the maintenance of hepatocyte-specific functions. The pharmaceutical industry has long awaited theExpand
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