K. Sengupta

Publications36
h-index17
Citations1,786
Highly Influential Citations91
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • R. Goldman
  • 374 Publications • 32,535 Citations
  • T. Ried
  • 559 Publications • 37,102 Citations
  • S. Linse
  • 374 Publications • 23,526 Citations
  • R. Foisner
  • 154 Publications • 11,961 Citations
  • Publications
  • Influence
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.
View on PubMed
Positional stability of single double-strand breaks in mammalian cells
TLDR
It is demonstrated that broken ends are positionally stable and unable to roam the cell nucleus, which supports a contact-first model in which chromosome translocations predominantly form among spatially proximal DSBs.
View on Nature
Nitroreductase-activated nitric oxide (NO) prodrugs.
View on PubMed
Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53
TLDR
Data show that Chk1 is critical for maintaining genome integrity and serves as a double-edged sword for cancer: although its inhibition kills cancer cells, it also triggers tumorigenesis when favorable mutations are accumulated for cell growth.
View on Nature
INDQ/NO, a bioreductively activated nitric oxide prodrug.
TLDR
Cell-based assays revealed that INDQ/NO induces DNA damage and is a potent inhibitor of cancer cell proliferation.
View on PubMed
Tumor Formation via Loss of a Molecular Motor Protein
View on Elsevier
HOXA repression is mediated by nucleoporin Nup93 assisted by its interactors Nup188 and Nup205
TLDR
This study reveals that the nucleoporin Nup93 assisted by its interactors Nup188 and Nup205 mediates the repression of HOXA gene expression.
View on Springer
Expression pattern of Drosophila translin and behavioral analyses of the mutant.
View on PubMed
Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus
TLDR
A remarkable interplay between Lamin A/C and Emerin in modulating cytoskeletal organization of actin and NM1 that impinges on chromatin dynamics and function in the interphase nucleus is underscore.
View on Springer
Artificially Introduced Aneuploid Chromosomes Assume a Conserved Position in Colon Cancer Cells
TLDR
Using 3D-FISH and confocal laser scanning microscopy, it is shown that Chromosomes 7, 18, or 19 introduced via microcell-mediated chromosome transfer into the parental diploid colon cancer cell line DLD-1 maintain their conserved position in the interphase nucleus.
View PDF
...
...