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Afferent connections of the laterodorsal and the pedunculopontine tegmental nuclei in the rat: A retro‐ and antero‐grade transport and immunohistochemical study
  • K. Semba, H. Fibiger
  • Biology, Medicine
  • The Journal of comparative neurology
  • 15 September 1992
Increasingly strong evidence suggests that cholinergic neurons in the mesopontine tegmentum play important roles in the control of wakefulness and sleep. To understand better how the activity ofExpand
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Multiple output pathways of the basal forebrain: organization, chemical heterogeneity, and roles in vigilance
  • K. Semba
  • Biology, Medicine
  • Behavioural Brain Research
  • 1 November 2000
Studies over the last decade have shown that the basal forebrain (BF) consists of more than its cholinergic neurons. The BF also contains non-cholinergic neurons, including gamma-aminobutyricExpand
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Effects of Ibotenate and 192IgG-Saporin Lesions of the Nucleus Basalis Magnocellularis/Substantia Innominata on Spontaneous Sleep and Wake States and on Recovery Sleep after Sleep Deprivation in Rats
The basal forebrain (BF) is known for its role in cortical and behavioral activation, and has been postulated to have a role in compensatory mechanisms after sleep loss. However, specific neuronalExpand
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Extent of colocalization of serotonin and GABA in the neurons of the rat raphe nuclei
Previous investigations of the distribution of neurons containing both serotonin and GABA in the brainstem raphe nuclei have yielded discrepant results amongst different authors. This study attemptedExpand
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Organization of HRP‐labeled trigeminal mandibular, primary afferent neurons in the rat
Horseradish peroxidase (HRP) applied to the transected mandibular division of the trigeminal (V) ganglion was transported anterogradely to pri‐mary afferent terminal zones in the dorsal andExpand
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Single cholinergic mesopontine tegmental neurons project to both the pontine reticular formation and the thalamus in the rat
Microinjections of the cholinergic agonist carbachol into a caudal part of the pontine reticular formation of the rat induce a rapid eye movement sleep-like state. This carbachol-sensitive region ofExpand
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Aminergic and cholinergic afferents to REM sleep induction regions of the pontine reticular formation in the rat
  • K. Semba
  • Biology, Medicine
  • The Journal of comparative neurology
  • 22 April 1993
Microinjection of cholinergic agonists in a dorsolateral part of the mesopontine tegmentum has been shown to induce a rapid eye movement (REM) sleep‐like state. Physiological evidence indicates thatExpand
  • 136
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The role of basal forebrain neurons in tonic and phasic activation of the cerebral cortex
The basal forebrain and in particular its cholinergic projections to the cerebral cortex have long been implicated in the maintenance of cortical activation. This review summarizes evidenceExpand
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Distribution of pituitary adenylate cyclase activating polypeptide (PACAP) immunoreactivity in the hypothalamus and extended amygdala of the rat
Pituitary adenylate cyclase activating polypeptide (PACAP) is found in two forms of 27 and 38 amino acids (PACAP‐27 and PACAP‐38 respectively) in the mammalian central nervous system. UsingExpand
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Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: Implications for the circadian control of behavioural state
The circadian clock housed in the suprachiasmatic nucleus (SCN) controls various circadian rhythms including daily sleep-wake cycles. Using dual tract-tracing, we recently showed that the medialExpand
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