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Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations.
UNLABELLED A consensus meeting was convened by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) to provide recommendations for interpreting clinical importanceExpand
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Recommendations for the pharmacological management of neuropathic pain: an overview and literature update.
The Neuropathic Pain Special Interest Group of the International Association for the Study of Pain recently sponsored the development of evidence-based guidelines for the pharmacological treatment ofExpand
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A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults.
BACKGROUND The incidence and severity of herpes zoster and postherpetic neuralgia increase with age in association with a progressive decline in cell-mediated immunity to varicella-zoster virusExpand
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A method for assessing drug therapy appropriateness.
This study evaluated the reliability of a new medication appropriateness index. Using the index, independent assessments were made of chronic medications taken by 10 ambulatory, elderly male patientsExpand
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Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations.
Chronic neuropathic pain, caused by lesions in the peripheral or central nervous system, comes in many forms. We describe current approaches to the diagnosis and assessment of neuropathic pain andExpand
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Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
Gene dosage of the apolipoprotein E (APOE) ε4 allele is a major risk factor for familial Alzheimer disease (AD) of late onset (after age 60). Here we studied a large series of 115 AD case subjectsExpand
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Recommendations for the management of herpes zoster.
The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact onExpand
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An Interdisciplinary Expert Consensus Statement on Assessment of Pain in Older Persons
This paper represents an expert-based consensus statement on pain assessment among older adults. It is intended to provide recommendations that will be useful for both researchers and clinicians.Expand
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Appropriate prescribing in elderly people: how well can it be measured and optimised?
Prescription of medicines is a fundamental component of the care of elderly people, and optimisation of drug prescribing for this group of patients has become an important public-health issueExpand
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Efficacy, safety, and tolerability of herpes zoster vaccine in persons aged 50-59 years.
BACKGROUND Herpes zoster (HZ) adversely affects individuals aged 50-59, but vaccine efficacy has not been assessed in this population. This study was designed to determine the efficacy, safety, andExpand
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