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Enzymatic Combustion of Aromatic and Aliphatic Compounds by Manganese Peroxidase from Nematoloma frowardii
ABSTRACT The direct involvement of manganese peroxidase (MnP) in the mineralization of natural and xenobiotic compounds was evaluated. A broad spectrum of aromatic substances were partiallyExpand
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Demonstration of Epstein-Barr virus in malignant non-Hodgkin's lymphomas.
Lymph nodes or tumor biopsies of 60 persons suspected of having a malignant lymphoma were examined for the presence of Epstein-Barr virus nuclear antigen (EBNA) by anticomplement immunofluorescence.Expand
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Bedeutung der Embolisierung der Arteria renalis für die Behandlung von Nierentumoren
In 24 patients with malignant kidney tumours percutaneous embolizations of the arteria renalis were performed in about 1 year. The material for embolization was gelatine-sponge-particles. TheExpand
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Metabolic activity testing can underestimate acute drug cytotoxicity as revealed by HepG2 cell clones overexpressing cytochrome P450 2C19 and 3A4.
Preclinical drug safety assessment includes in vitro studies with physiologically relevant cell cultures. As an in vitro system for hepatic toxicology testing, we have been generating cell clones ofExpand
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One-pot synthesis of human metabolites of SAR548304 by fungal peroxygenases.
Unspecific peroxygenases (UPOs, EC have proved to be stable oxygen-transferring biocatalysts for H2O2-dependent transformation of pharmaceuticals. We have applied UPOs in a drug developmentExpand
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Malignant lymphomas induced by an Epstein-Barr virus-related herpesvirus fromMacaca arctoides — a rabbit model
SummaryAnimal models for Epstein-Barr virus (EBV) are restricted to some species of new-world monkeys which develop malignant lymphoid tumours or benign lymphoproliferative diseases after virusExpand
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[Clinically unsuspected bronchial carcinoma in selected autopsy material].
During the period from January 1967 until December 1976, 8,503 adults and children (former inhabitants of the town of Erfurt) have been autopsied at the Institute of Pathology of the Medical AcademyExpand
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Back to “once a caesarean: always a caesarean”? A trend analysis in Switzerland
PurposeCaesarean sections (CS) have significantly increased worldwide and a previous CS is nowadays an important and increasingly reported indication to perform a repeat CS. There is a paucity ofExpand
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Side chain removal from corticosteroids by unspecific peroxygenase.
Two unspecific peroxygenases (UPO, EC from the basidiomycetous fungi Marasmius rotula and Marasmius wettsteinii oxidized steroids with hydroxyacetyl and hydroxyl functionalities at C17 -Expand
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Optimization of a biocatalytic process to gain (R)-1-phenylethanol by applying the software tool Sabento for ecological assessment during the early stages of development
Ecological assessment using the software tool Sabento was conducted to compare different processes to gain the fine chemical (R)-1-phenylethanol from ethylbenzene. The software was applied during theExpand
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