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Lumbar Ligamentum Flavum Hypertrophy Is Due to Accumulation of Inflammation-Related Scar Tissue
Study Design. A histologic, biologic, and immunohistochemical assessment using human samples of the lumbar ligamentum flavum. Objective. To prove our hypothesis that hypertrophy of the ligamentumExpand
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Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice.
In this study, we examined pathophysiological roles of osteoactivin, a functionally unknown type I membrane glycoprotein, in mouse skeletal muscle atrophied by denervation (sciatic neurectomy).Expand
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Union of defects in the pars interarticularis of the lumbar spine in children and adolescents. The radiological outcome after conservative treatment.
Lumbar spondylolysis can heal with conservative treatment, but few attempts have been made to identify factors which may affect union of the defects in the pars. We have evaluated, retrospectively,Expand
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Pathomechanism of Ligamentum Flavum Hypertrophy: A Multidisciplinary Investigation Based on Clinical, Biomechanical, Histologic, and Biologic Assessments
Study Design. A multidisciplinary study involving clinical, histologic, biomechanical, biologic, and immunohistologic approaches. Objective. To clarify the pathomechanism of hypertrophy of theExpand
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Effects of Charité Artificial Disc on the Implanted and Adjacent Spinal Segments Mechanics Using a Hybrid Testing Protocol
Study Design. Finite element model of L3–S1 segment and confirmatory cadaveric testing were used to investigate the biomechanical effects of a mobile core type artificial disc (Charité artificialExpand
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Athletes with Unilateral Spondylolysis are at Risk of Stress Fracture at the Contralateral Pedicle and Pars Interarticularis: A Clinical and Biomechanical Study
Background Unilateral spondylolysis is common in youths; its clinical and biomechanical features, especially effects on the contralateral side, are not fully understood. Hypothesis UnilateralExpand
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Biomechanical Rationale for Using Polyetheretherketone (PEEK) Spacers for Lumbar Interbody Fusion–A Finite Element Study
Study Design. To determine the effect of cage/spacer stiffness on the stresses in the bone graft and cage subsidence. Objective. To investigate the effect of cage stiffness on the biomechanics of theExpand
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Pathomechanism of Loss of Elasticity and Hypertrophy of Lumbar Ligamentum Flavum in Elderly Patients With Lumbar Spinal Canal Stenosis
Study Design. A histologic, biologic, and immunohistochemical assessment using human samples of lumbar ligamentum flavum. Objective. To clarify the pathomechanism of loss of elasticity andExpand
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Incidence of Lumbar Spondylolysis in the General Population in Japan Based on Multidetector Computed Tomography Scans From Two Thousand Subjects
Study Design. Epidemiological analysis using CTs. Objective. To investigate the true incidence of lumbar spondylolysis in the general population in Japan. Summary of Background Data. Although thereExpand
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Incidence and etiology of lumbar spondylolysis: review of the literature
BackgroundLumbar spondylolysis is a defect of the pars interarticularis known to occur as a stress fracture. Its incidence varies considerably depending on ethnicity, sex, and sports activity.Expand
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