• Publications
  • Influence
AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.
  • W. Lee, Mina Kim, +10 authors J. Park
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 3 February 2006
AMP-activated protein kinase (AMPK) activation increases fatty acid oxidation in skeletal muscle by decreasing malonyl CoA concentrations. However, this may not explain the long-term effects of AMPKExpand
  • 338
  • 22
Swim training improves leptin receptor deficiency-induced obesity and lipid disorder by activating uncoupling proteins
Leptin receptor deficiency causes morbid obesity and hyperlipidemia in mice. Since physical exercise enhances energy expenditure, it is an important part of successful weight-control regimens. WeExpand
  • 35
  • 2
CTRP1 protects against diet-induced hyperglycemia by enhancing glycolysis and fatty acid oxidation.
Complement-C1q/tumor necrosis factor-α related protein 1 (CTRP1) is a 35-kDa glycoprotein that is secreted from various tissues. Although CTRP1 is highly increased in patients with type II diabetesExpand
  • 19
  • 2
Expression of Protein Kinase C Genes in Normal (+/+) and W Mutant Alleles (Wsh/Wsh, W/Wv) Mice Testes
Abstract In the present study, we investigated the expression of mRNA of protein kinase C (PKC) isoenzymes (α, β, γ, δ, ε, ξ, and θ) in normal (+/+) and W mutant alleles mice testes. In +/+ miceExpand
  • 5
  • 2
The Korean traditional medicine Gyeongshingangjeehwan inhibits obesity through the regulation of leptin and PPARalpha action in OLETF rats.
Gyeongshingangjeehwan (GGEx), which comprises Liriope platyphylla F.T. Wang & T. Tang (Liliaceae), Platycodongrandiflorum A. DC. (Campanulaceae), Schisandrachinensis K. Koch (Magnoliaceae), andExpand
  • 44
  • 1
eNOS plays a major role in adiponectin synthesis in adipocytes.
  • E. Koh, Mina Kim, +9 authors K. Lee
  • Biology, Medicine
  • American journal of physiology. Endocrinology and…
  • 1 April 2010
Nitric oxide (NO) stimulates mitochondrial biogenesis. We recently reported that adiponectin synthesis is regulated by mitochondrial function in adipocytes. This study was undertaken to test theExpand
  • 44
  • 1
  • PDF
Liver PPARα and UCP2 are involved in the regulation of obesity and lipid metabolism by swim training in genetically obese db/db mice
Swim training for 6 weeks significantly decreased body weight gain, adipose tissue mass, and adipocyte size in both sexes of genetically obese db/db mice compared with their respective sedentaryExpand
  • 30
Increase in CIP2A expression is associated with doxorubicin resistance
The cancerous inhibitor of protein phosphatase 2A (CIP2A) increases the migration and metastasis of various cancer cells. Overexpression of CIP2A has been shown to increase the proliferation ofExpand
  • 51
  • PDF
The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.
Hyperlipidemia is a well-recognized risk factor for atherosclerosis and can be regulated by adipokines. Expression of the adipokine resistin-like molecule alpha (Retnla) is regulated by food intake;Expand
  • 26
  • PDF
Liver PPARalpha and UCP2 are involved in the regulation of obesity and lipid metabolism by swim training in genetically obese db/db mice.
Swim training for 6 weeks significantly decreased body weight gain, adipose tissue mass, and adipocyte size in both sexes of genetically obese db/db mice compared with their respective sedentaryExpand
  • 15