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Synthesis and biological evaluation of new derivatives of emodin.
- Lars Teich, K. S. Daub, Vera Krügel, Ludwig Nissler, R. Gebhardt, K. Eger
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 15 November 2004
Drugs containing an anthraquinone moiety such as daunorubicin (Daunoblastin) and mitoxantrone (Onkotrone) constitute some of the most powerful cytostatics. They suppress tumor growth mainly by… Expand
Synthesis of 3‐Aryloxy‐2‐iodoemodines by Oxidation of Emodin with (Diacetoxyiodo)arenes
Hypervalent iodine oxidation of emodin (1) with various (diacetoxyiodo)arenes 2a−f in potassium hydroxide/methanol leading to 3-aryloxy-1,8-dihydroxy-2-iodo-anthraquinones 4a−f is reported.… Expand