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Prioritising elective care: a cost utility analysis of orthopaedics in the north west of England.
TLDR
It is feasible to generate priority lists in a systematic way so that efficiency in health care purchasing can be achieved, and purchasers may use the results from these priority lists to help them maximise the benefits per unit of resource for their resident population.
Ambulance emergency services for patients with coronary heart disease in Lancashire: achieving standards and improving performance
TLDR
A significant improvement has been achieved in the performance of ambulance services in Lancashire since 1996, because of recently introduced strategies, notably RRVs, and in the presence of more demanding national standards and targets.
The subcellular distribution of rat liver L-alanine-glyoxylate aminotransferase in relation to a pathway for glucose formation involving glyoxylate.
TLDR
Subfractionation of the particles by differential sedimentation and on sucrose density gradients revealed a specific association between the aminotransferase and the mitochondrial enzymes glutamate dehydrogenase and rhodanese.
The effects of anti-leukaemic drugs on somatomedin production and cartilage responsiveness to somatomedin in vitro
TLDR
The poor growth of children with ALL during treatment may be mediated by a drug-induced combination of diminished somatomedin production and cartilage response to somatamedin.
Glycine metabolism in rat kidney cortex slices.
TLDR
It is concluded that glycine metabolism in rat kidney is largely via glycine cleavage closely coupled with serine formation, and that in the rat, potentially, the liver is quantitatively the more important organ in glycine catabolism.
The subcellular distribution of rat liver serine-pyruvate aminotransferase.
TLDR
Subfractionation of the particles by differential sedimentation and on sucrose density gradients showed a distribution for serine-pyruvate aminotransferase activity closely matching that observed for mitochondrial marker enzymes.
A difference in the incorporation of 14C into hippurate glycine from DL-(2-14C)-glutamate and DL-(5-14C)glutamate in guinea pigs.
TLDR
A hypothesis for glycine biosynthesis from l- glutamate is advanced, consistent with these findings, that includes conversion of l-glutamate to 4-hydroxy-2-oxoglutarate, the scission of the latter to glyoxylate and pyruvate, and the formation of glycine by transamination.
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