Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum.
The complete gene map described here includes genes for duplicated large and small subunit rRNAs, 25 species of tRNA, three subunits of a eubacterial RNA polymerase, 17 ribosomal proteins, and a translation elongation factor.
SufC hydrolyzes ATP and interacts with SufB from Thermotoga maritima
The Castes and Tribes of Southern India
THIS, if not quite the most workmanlike, may justly claim to be the most voluminous contribution to the publications of the Ethnographical Survey of India. The facts for which Mr. Thurston is…
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach.
It is demonstrated that N-myristoyltransferase is an essential and chemically tractable target in malaria parasites both in vitro and in vivo, and that selective inhibition of N- myristoylation leads to catastrophic and irreversible failure to assemble the inner membrane complex, a critical subcellular organelle in the parasite life cycle.
A simple method for isolating viable mature parasites of Plasmodium falciparum from cultures.
Control of malarial invasion by phosphorylation of the host cell membrane cytoskeleton
Evidence is presented that the activity of the membrane-associated cyclic AMP-independent kinase of the red blood cell is inseparable from invasion; the active substrate may be spectrin.
Antibiotic inhibitors of organellar protein synthesis in Plasmodium falciparum.
The evolutionary origin of the 35 kb circular DNA of Plasmodium falciparum: new evidence supports a possible rhodophyte ancestry
- D. Williamson, M. Gardner, P. Preiser, Daphne J. Moore, K. Rangachari, R. Wilson
- BiologyMolecular and General Genetics MGG
- 1 April 1994
A high degree of conservation confirms the 35 kb circle's plastid ancestry, and it is speculated that it may have originated from the rhodoplast of an ancient red algal endosymbiont in the progenitor of the Apicomplexa.
Targeting GFP to the malarial mitochondrion.
Sequence and organization of large subunit rRNA genes from the extrachromosomal 35 kb circular DNA of the malaria parasite Plasmodium falciparum.
- M. Gardner, J. Feagin, D. Moore, K. Rangachari, D. Williamson, R. Wilson
- Biology, MedicineNucleic acids research
- 11 March 1993
The malarial rRNA was found to be highly divergent in comparison with a selected group of chloroplast LSU rRNAs but was more closely related to them than to mitochondrial LSU rRNA genes.