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Analytical method development and validation of prasugrel in bulk and its pharmaceutical formulation using the RP-HPLC method
The proposed HPLC method is simple, fast, accurate, and precise for the simultaneous quantification of prasugrel in the dosage form, bulk drugs as well as for routine analysis in quality control.
RP-HPLC method for simultaneous estimation of Rosuvastatin and Ezetimibe from their combination tablet dosage form
Abstract Background Rosuvastatin is an HMG Co-A inhibitor and Ezetimibe is an intestinal cholesterol absorption inhibitor. The combination formulation is used for the treatment of…
Development and validation of HPLC method for determination of prasugrel in bulk and its pharmaceutical formulation
To develop and validate a simple, sensitive, precis e and specific reverse phase high performance liquid chromatographic method for the determination f prasugrel in bulk and tablet dosage forms. The…
Spectrophotometric Estimation of Abacavir Sulphate in Pharmaceutical Formulations
Two simple, accurate, rapid and sensitive methods (A and B) have been developed for the estimation of abacavir sulphate in its pharmaceutical dosage form. The method A and B are based on the…
Validated, reversed phase high performance liquid chromatography method for the estimation of atazanavir sulfate in pharmaceutical formulations
Reversed phase high performance liquid chromatographic method was developed and validated for estimation of Atazanavir Sulfate in tablet dosage form. A Sunfire C18, 250x4.6 mm i.d, 5 µm partical…
Simultaneous determination of dutasteride and tamsulosin in pharmaceutical dosage forms by RP-HPLC
A simple, rapid, precise and accurate isocratic reversed-phase HPLC method was developed and validated for the simultaneous determination of Dutasteride (DTA) and Tamsulosin (TMS) in commercial…
Estimation of Levetiracetam in Tablet Dosage Form by RP-HPLC
A simple, precise, rapid and accurate reverse phase HPLC method developed for the estimation of levetiracetam in tablet dosage form. A Sun Fire C18, 250 x 4.6 mm, 5 μm partical size, with mobile…
Acridone-pyrimidine hybrids- design, synthesis, cytotoxicity studies in resistant and sensitive cancer cells and molecular docking studies.
- M. Murahari, K. Prakash, G. Peters, Y. C. Mayur
- Chemistry, MedicineEuropean journal of medicinal chemistry
- 20 October 2017
Experimental data suggests that hybrid systems of acridone with substituted pyrimidines can be take as a lead for the design of efficient inhibitors and active compounds which can be taken up for further studies.
The estimation of gemcitabine hydrochloride in parenteral dosage forms by gradient RP-HPLC
A simple, precise, rapid and accurate reverse phase HPLC method developed for the estimation of Gemcitabine hydrochloride in parenteral dosage form. A Hypersil BDS C18, 150 x 4.6 mm, 5 µm particle…
Development and validation of LC-MS method for the determination of Rosuvastatin Hydrochloride in human plasma
A simple and sensitive liquid chromatography/tandem mass spectrometry method was developed and validated for determining rosuvastatin in human pla sma, a new synthetic hydroxyl methyl…