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Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction.
- H. Dehghani, M. Eames, +5 authors K. Paulsen
- Computer Science, Medicine
- Communications in numerical methods in…
- 1 June 2009
This paper outlines the main components of a software package, Near Infrared Fluorescence and Spectral Tomography (NIRFAST), which simulates light propagation in biological tissue based on the finite element method (FEM). Expand
A clinical prototype for active microwave imaging of the breast
Despite its recognized value in detecting and characterizing breast disease, X-ray mammography has important limitations that motivate the quest for alternatives to augment the diagnostic tools that… Expand
Automated region detection based on the contrast-to-noise ratio in near-infrared tomography.
The contrast-to-noise ratio (CNR) was used to determine the detectability of objects within reconstructed images from diffuse near-infrared tomography. It was concluded that there was a maximal value… Expand
Initial clinical experience with microwave breast imaging in women with normal mammography.
RATIONALE AND OBJECTIVES We have developed a microwave tomography system for experimental breast imaging. MATERIALS AND METHODS In this article, we illustrate a strategy for optimizing the coupling… Expand
Nonlinear Microwave Imaging for Breast-Cancer Screening Using Gauss–Newton's Method and the CGLS Inversion Algorithm
- T. Rubk, P. Meaney, P. Meincke, K. Paulsen
- IEEE Transactions on Antennas and Propagation
- 8 August 2007
Breast-cancer screening using microwave imaging is emerging as a new promising technique as a supplement to X-ray mammography. To create tomographic images from microwave measurements, it is… Expand
A computational model for tracking subsurface tissue deformation during stereotactic neurosurgery
- K. Paulsen, M.I. Miga, F. Kennedy, P.J. Hoopens, A. Hartov, D. Roberts
- Physics, Medicine
- IEEE Transactions on Biomedical Engineering
- 1 February 1999
We present a computational model of brain tissue deformation that could be used in conjunction with a limited amount of concurrently obtained operative data to estimate subsurface tissue motion. Expand
An octahedral shear strain-based measure of SNR for 3D MR elastography.
- M. McGarry, E. V. Van Houten, P. Perriñez, A. Pattison, J. Weaver, K. Paulsen
- Physics, Medicine
- Physics in medicine and biology
- 7 July 2011
A signal-to-noise ratio (SNR) measure based on the octahedral shear strain (the maximum shear strain in any plane for a 3D state of strain) is presented for magnetic resonance elastography (MRE),… Expand
Quantitative hemoglobin tomography with diffuse near-infrared spectroscopy: pilot results in the breast.
The authors describe what is, to the best of their knowledge, the first quantitative hemoglobin concentration images of the female breast that were formed with model-based reconstruction of… Expand
Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as an intraoperative biomarker.
OBJECT Accurate discrimination between tumor and normal tissue is crucial for optimal tumor resection. Qualitative fluorescence of protoporphyrin IX (PpIX), synthesized endogenously following… Expand
Fast 3-D Tomographic Microwave Imaging for Breast Cancer Detection
- T. Grzegorczyk, P. Meaney, P. Kaufman, R. diFlorio-Alexander, K. Paulsen
- Medicine, Computer Science
- IEEE Transactions on Medical Imaging
- 2 May 2012
Microwave breast imaging (using electromagnetic waves of frequencies around 1 GHz) has mostly remained at the research level for the past decade, gaining little clinical acceptance. Expand