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Pectin–gelatin and alginate–gelatin complex coacervation for controlled drug delivery: Influence of anionic polysaccharides and drugs being encapsulated on physicochemical properties of microcapsules
Abstract Microencapsulations using pectin and alginate by complex coacervation with gelatin were studied using metronidazole hydrochloride (MH), diclofenac sodium (DS) and indomethacin (IM) as core… Expand
Recent developments of collagen-based materials for medical applications and drug delivery systems.
- K. P. Rao
- Materials Science, Medicine
- Journal of biomaterials science. Polymer edition
In this review, an attempt was made to summarize some of the recent developments in the application of collagen as a biomaterial and in drug delivery systems. The main applications covered include:… Expand
Development of hydroxyapatite derived from Indian coral.
A simple method of converting the calcium carbonate skeleton of the corals available in the Indian coast into hydroxyapatite granules has been developed. By heating the coral to 900 degrees C, the… Expand
Nanoporous hydroxy-carbonate apatite scaffold made of natural bone
Abstract A processing method of hydroxy-carbonate apatite (HCAp) from the natural bone and their phase purity, crystal structure, chemical functionality, thermal stability, morphology, and solubility… Expand
Reduction of Calcification by Various Treatments in Cardiac Valves
The importance of glutaraldehyde pretreated bioprosthetic heart valves fabricated from bovine pericardium or porcine aortic valves is well realized in the management of valvular heart diseases. But,… Expand
Heat-deproteinated xenogeneic bone from slaughterhouse waste: Physico-chemical properties
Xenogeneic bone procured from the slaughterhouse waste was deproteinated by heat treatment method intended for use as a bone substitute. The effect of heat treatment was investigated by thermal… Expand
Tailor-made chitosans for drug delivery
Graft copolymers of chitosan were prepared using acrylic and methacrylic acids. The grafting was initiated by eerie ion. Experimental parameters such as the concentrations of monomer and the… Expand
Fluorinated bovine hydroxyapatite: preparation and characterization
Chemically and thermally treated bovine bone has been proposed as an alternative to bone grafts and synthetic bone substitutes. Fluorinated bovine hydroxyapatite (FBHA) was prepared by two different… Expand
Biodegradable microspheres using two different gelatin drug conjugates for the controlled delivery of methotrexate
Abstract The anticancer drug methotrexate (MTX) was covalently linked to gelatin by the azide coupling-grafting method. Two gelatin-MTX conjugates were prepared by coupling (i) MTX azide to gelatin… Expand
Collagen-chitosan polymeric scaffolds for the in vitro culture of human epidermoid carcinoma cells.
- N. Shanmugasundaram, P. Ravichandran, P. N. Reddy, N. Ramamurty, S. Pal, K. P. Rao
- Materials Science, Medicine
A biodegradable polymer scaffold was developed using collagen and chitosan, in the form of interpenetrating polymeric network (IPN), for in vitro culture of human epidermoid carcinoma cells (HEp-2,… Expand