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Structural study of a new antitumor antibiotic, kazusamycin.
TLDR
The structure of a new antitumor antibiotic produced by Streptomyces sp. Expand
Antitumor activity of leptomycin B.
Antitumor activity of a new antibiotic, kazusamycin.
TLDR
There was no clear dose response for the efficacy of kazusamycin on murine tumors, however the cytotoxicity of the antibiotic depended on the incubation time. Expand
Structure of trienomycin A, a novel cytocidal ansamycin antibiotic.
Studies on a novel cytocidal antibiotic, trienomycin A. Taxonomy, fermentation, isolation, and physico-chemical and biological characteristics.
TLDR
Trienomycin A showed no antimicrobial activity against the bacteria, fungi and yeasts examined with the exception of weak activity versus Piricularia oryzae at a concentration of 1,000 micrograms/ml. Expand
Structures of trienomycins A, B and C, novel cytocidal ansamycin antibiotics.
TLDR
Trienomycins showed no antimicrobial activity against the bacteria, fungi and yeasts examined with the exception of weak activity versus Piricularia oryzae at a concentration of 1,000 micrograms/ml. Expand
A new antitumor antibiotic, kazusamycin.
A new antibiotic kazusamycin, was isolated from the culture broth of Streptomyces sp. No. 81-484, which shows antitumor activity against experimental murine tumors. This antibiotic did not possessExpand
Bioconversion of FR901459, a novel derivative of cyclosporin A, by Lentzea sp. 7887
TLDR
Findings suggest that strain 7887 can be used to derivative FR901459 to produce a chemical template for further chemical modifications that may provide more effective and safer anti-HCV drugs. Expand
Structure of awamycin, a novel antitumor ansamycin antibiotic.
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