K. Nishimura

Publications231
h-index27
Citations2,408
Highly Influential Citations117
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Conventional multiple or microdissection testicular sperm extraction: a comparative study.
BACKGROUND Testicular sperm extraction (TESE) with ICSI is becoming the first-line treatment for non-obstructive azoospermia (NOA). Recently, the sperm retrieval rate (SRR) by microdissection TESE… Expand
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Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator.
The partial agonist effect of antiandrogens has been well documented, and such effect is amplified by derived mutant androgen receptors (ARs) in prostate cancer cells. Here we report the… Expand
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Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation.
PURPOSE Tumor associated macrophages can regulate the growth of various cancers positively or negatively. Intravesical bacillus Calmette-Guerin instillation is now gold standard treatment for bladder… Expand
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KIT (c-kit oncogene product) pathway is constitutively activated in human testicular germ cell tumors.
We investigated the expression of KIT (product of c-kit oncogene), gain-of-function mutations, and activation of its downstream signal transduction in human testicular cancers. KIT was expressed in… Expand
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Long-term results of surgical resection for pulmonary metastasis from renal cell carcinoma: a 25-year single-institution experience.
OBJECTIVE Despite the report of new treatment options, surgery remains the best treatment for pulmonary metastases from renal cell carcinoma (RCC). Repeat resection is also an effective means for… Expand
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Chromosomal variants among 1790 infertile men
Abstract Background: The largest cytogenetic survey involving infertile men was undertaken to clarify whether chromosomal abnormalities, including autosomal abnormalities, affect semen qualities.
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Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF‐κB
The transcription factor nuclear factor‐κB (NF‐κB) has been shown to be constitutively activated in various human malignancies, including leukemia, lymphoma and a number of solid tumors. NF‐κB… Expand
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Anticarcinogenic effect of FTY720 in human prostate carcinoma DU145 cells: Modulation of mitogenic signaling, FAK, cell‐cycle entry and apoptosis
Despite the high frequency of prostate cancer, therapeutic options for advanced disease are limited to chemotherapy, radiation or hormonal therapy and eventually fail in all patients. Therefore,… Expand
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Surveillance following orchiectomy for stage I testicular seminoma: Long‐term outcome
Objectives:  To report the long‐term outcome of surveillance for stage I seminoma at a single institution in Japan.
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One-month relative dose intensity of not less than 50% predicts favourable progression-free survival in sorafenib therapy for advanced renal cell carcinoma in Japanese patients.
BACKGROUND Sorafenib is a multikinase inhibitor used as a second-line treatment for metastatic renal cell carcinoma (mRCC). However, it is very difficult to estimate sorafenib dosage because it is… Expand
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