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Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D
Small, compact genomes of ultrasmall unicellular algae provide information on the basic and essential genes that support the lives of photosynthetic eukaryotes, including higher plants. Here weExpand
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Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
INTRODUCTION To combat invading pathogens, cells develop an adaptive immune response by changing their own genetic information. In vertebrates, the generation of genetic variation (somaticExpand
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A Plant-Specific Dynamin-Related Protein Forms a Ring at the Chloroplast Division Site Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.009373.
Chloroplasts have retained the bacterial FtsZ for division, whereas mitochondria lack FtsZ except in some lower eukaryotes. Instead, mitochondrial division involves a dynamin-related protein,Expand
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A 100%-complete sequence reveals unusually simple genomic features in the hot-spring red alga Cyanidioschyzon merolae
BackgroundAll previously reported eukaryotic nuclear genome sequences have been incomplete, especially in highly repeated units and chromosomal ends. Because repetitive DNA is important for manyExpand
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Early increases in TNF-α, IL-6 and IL-1β levels following transient cerebral ischemia in gerbil brain
Abstract The effects of transient global ischemia using bilateral carotid artery occlusion on regional cytokine levels in gerbil brain were investigated using enzyme-linked immunoassay techniques.Expand
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Two Types of FtsZ Proteins in Mitochondria and Red-Lineage Chloroplasts: The Duplication of FtsZ Is Implicated in Endosymbiosis
The ancestors of plastids and mitochondria were once free-living bacteria that became organelles as a result of endosymbiosis. According to this theory, a key bacterial division protein, FtsZ, playsExpand
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Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
We applied a fusion of CRISPR-Cas9 and activation-induced cytidine deaminase (Target-AID) for point mutagenesis at genomic regions specified by single guide RNAs (sgRNAs) in two crop plants. In rice,Expand
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An evolutionary puzzle: chloroplast and mitochondrial division rings.
Consistent with their bacterial origin, chloroplasts and primitive mitochondria retain a FtsZ ring for division. However, chloroplasts and mitochondria have lost most of the proteins required forExpand
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Development of a comprehensive set of tools for genome engineering in a cold- and thermo-tolerant Kluyveromyces marxianus yeast strain
Kluyveromyces marxianus, a non-conventional thermotolerant yeast, is potentially useful for production of ethanol and other products. This species has a strong tendency to randomly integrateExpand
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Dynamic recruitment of dynamin for final mitochondrial severance in a primitive red alga
Dynamins are a eukaryote-specific family of GTPases. Some family members are involved in diverse and varied cellular activities. Here, we report that the primitive red alga Cyanidioschyzon merolaeExpand
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