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Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium.
BACKGROUND Ocular trauma or disease may lead to severe corneal opacification and, consequently, severe loss of vision as a result of complete loss of corneal epithelial stem cells. Transplantation ofExpand
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Human limbal epithelium contains side population cells expressing the ATP‐binding cassette transporter ABCG2
Many types of organ‐specific stem cells have been recently shown to exhibit a side population (SP) phenotype based on their ability to efflux Hoechst 33342 dye. Because stem cells from cornealExpand
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Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene
Macular corneal dystrophy (MCD; MIM 217800) is an autosomal recessive hereditary disease in which progressive punctate opacities in the cornea result in bilateral loss of vision, eventuallyExpand
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Identification of the gene responsible for gelatinous drop-like corneal dystrophy
Gelatinous drop-like corneal dystrophy (GDLD; OMIM 204870) is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness, with an incidence of 1 in 300,000 inExpand
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Circadian changes in subfoveal choroidal thickness and the relationship with circulatory factors in healthy subjects.
PURPOSE To investigate circadian changes in subfoveal choroidal thickness (SFCT) and the relation to systemic factors in healthy subjects. METHODS Thirty-eight eyes of 19 healthy volunteers wereExpand
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Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice.
During development, the retinal vasculature grows toward hypoxic areas in an organized fashion. By contrast, in ischemic retinopathies, new blood vessels grow out of the retinal surfaces withoutExpand
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Global Consensus on Keratoconus and Ectatic Diseases
Background: Despite extensive knowledge regarding the diagnosis and management of keratoconus and ectatic corneal diseases, many controversies still exist. For that reason, there is a need forExpand
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Choroidal observations in Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography
BackgroundThe aim of this work was to investigate the choroidal morphologic changes of Vogt–Koyanagi–Harada (VKH) disease in vivo using high-penetration optical coherence tomography (HP-OCT) with aExpand
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Evaluation of LOXL1 polymorphisms in eyes with exfoliation glaucoma in Japanese
Purpose To investigate the lysyl oxidase-like 1 (LOXL1) gene for single nucleotide polymorphism (SNP) variations in Japanese patients with exfoliation syndrome (XFS) and exfoliation glaucoma (XFG)Expand
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Reproducibility of retinal and choroidal thickness measurements in enhanced depth imaging and high-penetration optical coherence tomography.
PURPOSE Two optical coherence tomography (OCT) modalities can visualize the choroid: high-penetration OCT (HP-OCT) using a long wavelength, and enhanced depth imaging technique using Heidelberg OCTExpand
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