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- Publications
- Influence
Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis.
- T. Wallimann, M. Wyss, D. Brdiczka, K. Nicolay, H. Eppenberger
- Biology, Medicine
- The Biochemical journal
- 1992
Biexponential diffusion attenuation in various states of brain tissue: Implications for diffusion‐weighted imaging
- T. Niendorf, R. Dijkhuizen, D. Norris, M. van Lookeren Campagne, K. Nicolay
- Chemistry, Medicine
- Magnetic resonance in medicine
- 1 December 1996
Diffusion‐weighted single voxel experiments conducted at b‐values up to 1 × 104 smm−2 yielded biexponential signal attenuation curves for both normal and ischemic brain. The relative fractions of the… Expand
1H MR spectroscopy of the brain: absolute quantification of metabolites.
- J. Jansen, W. Backes, K. Nicolay, M. E. Kooi
- Medicine
- Radiology
- 1 August 2006
Hydrogen 1 (1H) magnetic resonance (MR) spectroscopy enables noninvasive in vivo quantification of metabolite concentrations in the brain. Currently, metabolite concentrations are most often… Expand
Characterization of the normal cardiac myofiber field in goat measured with MR-diffusion tensor imaging.
- L. Geerts, P. Bovendeerd, K. Nicolay, T. Arts
- Materials Science, Medicine
- American journal of physiology. Heart and…
- 1 July 2002
Cardiac myofiber orientation is a crucial determinant of the distribution of myocardial wall stress. Myofiber orientation is commonly quantified by helix and transverse angles. Accuracy of reported… Expand
Diffusion NMR spectroscopy
- K. Nicolay, K. Braun, R. A. Graaf, R. Dijkhuizen, M. Kruiskamp
- Chemistry, Medicine
- NMR in biomedicine
- 1 April 2001
MR offers unique tools for measuring molecular diffusion. This review focuses on the use of diffusion‐weighted MR spectroscopy (DW‐MRS) to non‐invasively quantitate the translational displacement of… Expand
Neuroprotection by the Endogenous Cannabinoid Anandamide and Arvanil against In Vivo Excitotoxicity in the Rat: Role of Vanilloid Receptors and Lipoxygenases
- W. Veldhuis, M. van der Stelt, +8 authors V. Di Marzo
- Chemistry, Medicine
- The Journal of Neuroscience
- 15 May 2003
Type 1 vanilloid receptors (VR1) have been identified recently in the brain, in which they serve as yet primarily undetermined purposes. The endocannabinoid anandamide (AEA) and some of its oxidative… Expand
In vivo 31P-NMR diffusion spectroscopy of ATP and phosphocreatine in rat skeletal muscle
- R. A. Graaf, A. V. Kranenburg, K. Nicolay
- Chemistry
- 1 April 2000
The aim of this study was to measure the diffusion of ATP and phosphocreatine (PCr) in intact rat skeletal muscle, using (31)P-NMR. The acquisition of the diffusion-sensitized spectra was optimized… Expand
Exogenous Anandamide Protects Rat Brain against Acute Neuronal Injury In Vivo
- M. van der Stelt, W. Veldhuis, +7 authors K. Nicolay
- Medicine
- The Journal of Neuroscience
- 15 November 2001
The endocannabinoid anandamide [N-arachidonoylethanolamine (AEA)] is thought to function as an endogenous protective factor of the brain against acute neuronal damage. However, this has never been… Expand
Intramyocellular lipid content is increased after exercise in nonexercising human skeletal muscle.
- V. Schrauwen-Hinderling, L. V. van Loon, R. Koopman, K. Nicolay, W. Saris, M. E. Kooi
- Chemistry, Medicine
- Journal of applied physiology
- 2003
Intramyocellular lipid (IMCL) content has been reported to decrease after prolonged submaximal exercise in active muscle and, therefore, seems to form an important local substrate source. Because… Expand
The increase in intramyocellular lipid content is a very early response to training.
- V. Schrauwen-Hinderling, P. Schrauwen, +5 authors M. E. Kooi
- Chemistry, Medicine
- The Journal of clinical endocrinology and…
- 1 April 2003
The present study investigated the influences of a 2-wk training program on intramyocellular lipid (IMCL) content, IMCL decrease during exercise, fat oxidation, and insulin sensitivity. Nine… Expand