• Publications
  • Influence
Evidence that dynorphin-(1-13) acts as an agonist on opioid kappa-receptors.
TLDR
The data indicate that dynorphin-(1-13) acts as an endogenous agonist on kappa-receptors, and Mr 2266 was found to be several-fold more effective than naloxone to antagonize the agonist actions of both kappa. Expand
Evidence that dynorphin-(1–13) acts as an agonist on opioid κ-receptors
Abstract The study concerned the opioid-receptor subtype on which dynorphin-(1–13) acts in in vitro isolated preparations. The potency of dynorphin-(1–13) relative to that of ethylketocyclazocine (MrExpand
The choice of opiate receptor subtype by neo-endorphins.
TLDR
The data indicate that neo-endorphins act as kappa-receptor agonists in either the guinea-pig and rabbit ileum or in the rabbit vas deferens while in the mouse vasdeferens they act on opiate receptor subtypes other than kappa - and mu-receptors. Expand
Effect of neurohumoral modulators on the morphine-induced hyperthermia in non-tolerant rats.
  • T. Oka, K. Negishi
  • Chemistry, Medicine
  • European journal of pharmacology
  • 7 April 1977
TLDR
The results suggest that morphine causes hyperthermia in some strains of rats by a cholinergic mechanism and the involvement of an adrenergic or serotonergic mechanism in this case appears unlikely. Expand
Evidence that endogenous 6-(Arg or Lys)-opioid peptides can interact with κ-receptors as agonists
Abstract Evidence is provided for the abilities of endogenous 6-(Arg or Lys)-opioid peptides to interact with κ-receptors as agonists. Dynorphin-(1–17) and -(1–8), α- and β-neo-endorphin, [Met 5Expand
EFFECTS OF OPIOID PEPTIDES AND KAPPA-RECEPTOR AGONISTS ON IN VITRO ISOLATED PREPARATIONS
Evidences that dynorphin-(1–13) acted as kappa-receptor agonist and that rabbit and dog ileum contained the new type of opiate receptor which was tentatively termed iota receptor, were obtained byExpand
Opioid receptor subtype in isolated preparations.
Abstract It is well-known that the guinea-pig ileum and the mouse vas deferens contain opioid receptors,and they have been widely employed as a suitable preparation for opioid study. In contrast, theExpand
Evidence that endogenous 6-(ARG or LYS)-opioid peptides can interact with kappa-receptors as agonists.
TLDR
Data in the present study suggest that endogenous opioid peptides can be classified into two groups in terms of an ability to interact with kappa-receptors as an agonist. Expand
...
1
2
...