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Analytical Method Development and Validation for HPLC-ECD Determination of Moxifloxacin in Marketed Formulations
An HPLC-ECD analytical method with high reproducibility and wide linearity range has been developed and validated. Moxifloxacin was separated and identified using this method with a simple mobileExpand
Mutational landscape and in silico structure models of SARS-CoV-2 Spike Receptor Binding Domain reveal key molecular determinants for virus-host interaction
TLDR
Key molecular arrangements in RBD-ACE2 interface that help virus to tolerate mutations and prevail are identified that are indispensable to anchor RBD and well conserved in all SARS-like corona viruses. Expand
Quantification of Sofosbuvir in Human Plasma: RP-HPLC Method Development and Validation
Sofosbuvir, a potential inhibitor of the nucleotide analog of hepatitis C virus (HCV) NS5B polymerase, is used to treat hepatitis C and marketed under brand name Sovaldi. This study was aimed toExpand