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S gene expression and the timing of lysis by bacteriophage lambda.
The S gene of bacteriophage lambda encodes the holin required for release of the R endolysin at the onset of phage-induced host lysis. S is the promoter-proximal gene on the single lambda lateExpand
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Dual translational initiation sites control function of the lambda S gene.
Lysis gene S of phage lambda has a 107 codon reading frame beginning with the codons Met1‐Lys2‐Met3. Genetic data have suggested that translational initiation occurs at both Met1 and Met3, generatingExpand
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The lethal lambda S gene encodes its own inhibitor.
The 107 codon reading frame of the lambda lysis gene S begins with the codon sequence Met1‐Lys2‐Met3..., and it has been demonstrated in vitro that both Met codons are used for translational starts.Expand
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Severe growth defect in a Schizosaccharomyces pombe mutant defective in intron lariat degradation.
The cDNAs and genes encoding the intron lariat-debranching enzyme were isolated from the nematode Caenorhabditis elegans and the fission yeast Schizosaccharomyces pombe based on their homology withExpand
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Yeast lariat debranching enzyme. Substrate and sequence specificity.
Yeast RNA lariat debranching enzyme has been purified to near homogeneity using a bacterial overproducer of the enzyme. The enzyme is capable of digesting a variety of branched nucleic acidExpand
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Human RNA lariat debranching enzyme cDNA complements the phenotypes of Saccharomyces cerevisiae dbr1 and Schizosaccharomyces pombe dbr1 mutants.
The cDNA encoding the human RNA lariat debranching enzyme (hDBR1) was identified and cloned by searching the Expressed Sequence Tag (EST) database and screening a HeLa cDNA library, based onExpand
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RNA lariat debranching enzyme.
Publisher Summary Wallace and Edmonds first discovered branched nucleic acids in the population of nuclear polyadenylated RNAs. These branched nucleic acids are mostly derived from intron lariats,Expand
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Conservation of a dual-start motif in P22 lysis gene regulation.
Gene 13 of bacteriophage P22 is functionally equivalent to lambda lysis gene S. Gene S codes for two products, the polypeptides S105 and S107, produced from translational initiation events at theExpand
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Translational efficiency of phi X174 lysis gene E is unaffected by upstream translation of the overlapping gene D reading frame.
The lysis gene E of bacteriophage phi X174 is entirely embedded in gene D. Expression studies of genes D and E in Escherichia coli minicells and lysis times obtained in the presence or absence of DExpand
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Synthesis of two bacteriophage lambda S proteins in an in vivo system.
Bacteriophage lambda has two genes which are essential for lysis: R, a gene encoding a 158-amino-acid (aa) transglycosylase that attacks the peptidoglycan, and S, a gene encoding twoExpand
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