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Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation.
Some exogenous antigens, such as heat shock proteins or apoptotic bodies, gain access to the MHC class I processing pathway and initiate CTL responses, a process called cross-priming. To be efficientExpand
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The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells.
The low affinity receptor for IgG, FcgammaRIIB, functions to dampen the antibody response and reduce the risk of autoimmunity. This function is reportedly mediated in part by inhibition of B cellExpand
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Cardiac fibrosis in mice lacking brain natriuretic peptide.
Cardiac fibrosis, defined as a proliferation of interstitial fibroblasts and biosynthesis of extracellular matrix components in the ventricles of the heart, is a consequence of remodeling processesExpand
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Lectin-like oxidized LDL receptor-1 is a cell-adhesion molecule involved in endotoxin-induced inflammation
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a major endothelial receptor for oxidized low-density lipoprotein, and is assumed to play a proatherogenic role in atherosclerosis.Expand
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Characterization of Plasmodium falciparum sporozoite surface protein 2.
Immunization of mice with Plasmodium yoelii sporozoite surface protein 2 (PySSP2) and circumsporozoite protein protects completely against P. yoelii. The amino acid sequence of PySSP2 suggested thatExpand
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Full-term development of mouse blastomere nuclei transplanted into enucleated two-cell embryos.
The nuclei from four- and eight-cell mouse embryos were transplanted into enucleated two-cell embryos. It was found that such embryos not only developed to the blastocyst stage in vitro (72% andExpand
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Centrosome abnormalities in pancreatic ductal carcinoma.
The centrosome plays an important role in microtubule nucleation and organization, ensuring the establishment of cell polarity and balanced chromosome segregation. Recent studies have suggested thatExpand
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Fc gammaRIIB1 inhibition of BCR-mediated phosphoinositide hydrolysis and Ca2+ mobilization is integrated by CD19 dephosphorylation.
The B cell receptor for immunoglobulin G, Fc gammaRIIB1, is a potent transducer of signals that block antigen-induced B cell activation. Coligation of Fc gammaRIIB1 with B lymphocyte antigenExpand
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Early weaning augments neuroendocrine stress responses in mice
Weaning is one of the most important events in early mammalian life. We investigated the influence of early weaning on the development of neuroendocrine responses to stress in mice. Our studyExpand
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Characterization of multiple Chinese hamster carbonyl reductases.
Carbonyl reductase (CR) is an enzyme which can catalyze the oxidoreduction of various carbonyl compounds in the presence of NAD(P)H. With the PCR method, using primers carrying the conservedExpand
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