• Publications
  • Influence
Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity
Coumarin (2H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral,Expand
  • 404
  • 16
  • PDF
Repurposing of FDA-approved antivirals, antibiotics, anthelmintics, antioxidants, and cell protectives against SARS-CoV-2 papain-like protease
Abstract SARS-CoV-2 or Coronavirus disease 19 (COVID-19) is a rapidly spreading, highly contagious, and sometimes fatal disease for which drug discovery and vaccine development are critical.Expand
  • 15
  • 2
Concomitant polymorphism in 3-acetylcoumarin: role of weak C-H···O and C-H···π interactions
An analysis of structural features associated with polymorphism in 3-acetylcoumarin has been made in terms of morphology, infrared spectroscopy, crystal structure, powder X-ray diffraction, and dif...
  • 62
  • 1
Microwave-Induced Synthesis of Schiff Bases of Aminothiazolyl Bromocoumarins as Antibacterials
A fast and highly efficient method for the synthesis of some of the schiff bases of aminothiazolylbromocoumarin (4a-m) has been performed by microwave irradiation ofExpand
  • 59
  • 1
Quantitative Analysis of Intermolecular Interactions in 7-Hydroxy-4-methyl-2H-chromen-2-one and Its Hydrate
The determination of the crystal and molecular structure of organic compounds has contributed immensely towards the area of crystal engineering. This contributes towards the understanding of theExpand
  • 6
  • 1
  • PDF
Nanoparticle formulation by Büchi B-90 Nano Spray Dryer for oral mucoadhesion
Diabetes is considered one of the main threats to global public health in this era. It is increasing rapidly in every part of the world; the prevalence of the disease will grow to the point where 366Expand
  • 22
  • 1
  • PDF
Protective Effect of Spirulina platensis Extract against Dextran-Sulfate-Sodium-Induced Ulcerative Colitis in Rats
Inflammatory bowel disease is a multifactorial inflammatory condition. This study aimed to test the protective effects of Spirulina platensis against ulcerative colitis (UC). UC was induced inExpand
  • 9
  • 1
  • PDF
Graphene-based hybrid nanoparticle of doxorubicin for cancer chemotherapy
Background Prostate cancer (PC) has the highest prevalence in men and accounts for a high rate of neoplasia-related death. Doxorubicin (DOX) is one of the most widely used anti-neoplastic drugs forExpand
  • 9
  • 1
  • PDF
Novel Drying Technology of Microsphere and Its Evaluation for Targeted Drug Delivery for Lungs
Carbopol microspheres of methotrexate (MxtCM), a drug used in the treatment of lung cancer, were prepared using a Buchi B-90 nano spray dryer. The surface morphology was found to be shriveled toExpand
  • 9
  • 1
Ethyl 4-(4-chlorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
TLDR
In the title compound, C14H15ClN2O2S, the tetrahydropyrimidine ring adopts a twisted boat conformation with the carbonyl group in an s-trans conformation and is stabilized by an intramolecular C—H⋯π interaction. Expand
  • 5
  • 1
  • PDF