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Comparison of hyperventilation and inhaled nitric oxide for pulmonary hypertension after repair of congenital heart disease
BackgroundPulmonary hypertension is associated with congenital heart lesions with increased pulmonary blood flow. Acute increases in pulmonary vascular resistance (PVR) occur in the postoperativeExpand
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Distribution of pulmonary blood flow in the perfluorocarbon-filled lung
Objective: Partial liquid ventilation (PLV) improves gas exchange in animal studies of lung injury. Perfluorocarbons (PFCs) are heavy liquids and are therefore preferentially delivered to the mostExpand
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Hypothermia Pediatric Head Injury Trial: The Value of a Pretrial Clinical Evaluation Phase
Background: The utility of a pretrial clinical evaluation or run-in phase prior to conducting trials of complex interventions such as hypothermia therapy following severe traumatic brain injury inExpand
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Inhaled nitric oxide differentiates pulmonary vasospasm from vascular obstruction after surgery for congenital heart disease
Objective: To evaluate whether a trial of inhaled nitric oxide (NO) differentiates reversible pulmonary vasoconstriction from fixed anatomic obstruction to pulmonary blood flow after surgery forExpand
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RELATIVE DISTRIBUTION OF GAS AND PERFLUOROCARBON (PFC) DURING PARTIAL LIQUID VENTILATION (PLV). ▴ 258
RELATIVE DISTRIBUTION OF GAS AND PERFLUOROCARBON (PFC) DURING PARTIAL LIQUID VENTILATION (PLV). ▴ 258
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Effect of a sustained inflation on regional distribution of gas and perfluorocarbon during partial liquid ventilation
To study the effect of a sustained inflation (SI) maneuver on the regional distribution of gas and perfluorocarbon (PFC) during partial liquid ventilation (PLV) in normal pigs using computerizedExpand
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Perfluorocarbon and accuracy of tidal volume estimation.
We read with interest the report by Dr. Devabhaktuni and colleagues (1) on the effect of nitric oxide, perfluorocarbon, and heliox on differential pressure pneumotachometer characteristics. We haveExpand
Distribution of Gas and Flurocarbon Measured by CT Densitometry. 42
Hypothesis: Partial liquid ventilation uses flurocarbons (PFC) which have a great capacity for O2 and CO2 but also present a major diffusion barrier. Therefore, effective gas exchange requires aExpand