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Delayed diagnosis of Duchenne muscular dystrophy.
TLDR
In the absence of a national newborn screening programme for Duchenne muscular dystrophy, all health care professionals should be made more aware of the condition and have a lower threshold for measuring a creatine phosphokinase level. Expand
A Quality Improvement Project to Reduce the ‘No Show’ rate in a Paediatric Neurology Clinic
TLDR
Following three intervention PDSAs, mainly addressing communication and appointment flexibility, the post intervention no-show rate dropped to 18% and was sustained below the target of 25% for two years. Expand
Efficacy and tolerability of topiramate in childhood and adolescent epilepsy: a clinical experience
TLDR
The drug appeared to be most effective in children with moderate learning difficulties with 75% showing an improvement in seizure control compared with 25% of children with normal educational functioning, and topiramate was withdrawn in 25 patients. Expand
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
TLDR
Although ethosuximide, lamotrigine and valproate are commonly used to treat people with absence seizures, there is insufficient evidence to inform clinical practice, and the few trials included were of poor methodological quality and did not have sufficient number of participants. Expand
A systematic review of treatment of typical absence seizures in children and adolescents with ethosuximide, sodium valproate or lamotrigine
TLDR
A systematic review of randomized controlled trials that included children or adolescents with typical absence seizures who received treatment with ethosuximide, sodium valproate or lamotrigine found no reliable evidence to inform clinical practice. Expand
Enoxaparin and aspirin therapy for recurrent pregnancy loss due to anti-phospholipid syndrome (APS)
TLDR
Use ofLow dose aspirin and enoxaparin 40 mg subcutaneously daily in patients with RPL due to antiphospholipid syndrome resulted in higher live birth rates compared to low dose aspirin alone. Expand
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
TLDR
Although ethosuximide, lamotrigine and valproate are commonly used to treat people with absence seizures, there is insufficient evidence to inform clinical practice, and the few trials included were of poor methodological quality. Expand
Calcium Dobesilate versus Cabergoline for Prevention of Ovarian HyperStimulation Syndrome
TLDR
Calcium dobesilate (CaD) was more effective in preventing severe OHSS and decreasing OHSS occurrence rates than cabergoline when used in highrisk patients. Expand
Diosmin versus cabergoline for prevention of ovarian hyperstimulation syndrome
TLDR
It was concluded that diosmin was more effective in preventing severe OHSS and decreasing OHSS occurrence rates than cabergoline when used in high-risk patients. Expand
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