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- Publications
- Influence
Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance.
- M. Tabata, T. Kadomatsu, +23 authors Y. Oike
- Biology, Medicine
- Cell metabolism
- 2 September 2009
Recent studies of obesity have provided new insights into the mechanisms underlying insulin resistance and metabolic dysregulation. Numerous efforts have been made to identify key regulators of… Expand
Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia
- A. Beigneux, K. Miyashita, +22 authors S. Young
- Medicine
- The New England journal of medicine
- 5 April 2017
BACKGROUND A protein that is expressed on capillary endothelial cells, called GPIHBP1 (glycosylphosphatidylinositol‐anchored high‐density lipoprotein binding protein 1), binds lipoprotein lipase and… Expand
Novel sandwich ELISA for human angiotensinogen.
- A. Katsurada, Y. Hagiwara, +5 authors H. Kobori
- Chemistry, Medicine
- American journal of physiology. Renal physiology
- 6 June 2007
We recently reported that urinary excretion rates of angiotensinogen (U(AGT)) provide a specific index of intrarenal renin-angiotensin (ANG) system (RAS) status in ANG II-dependent hypertensive rats.… Expand
Sensitive and Specific New Enzyme-Linked Immunosorbent Assay for N-ERC/Mesothelin Increases its Potential as a Useful Serum Tumor Marker for Mesothelioma
- K. Shiomi, Yoshiaki Hagiwara, +16 authors O. Hino
- Medicine
- Clinical Cancer Research
- 1 March 2008
Background: Because mesothelioma initially progresses on the surface of the pleura and peritoneum without forming masses, it has been difficult to diagnose at an early stage. It would be very useful… Expand
Association of circulating ANGPTL 3, 4, and 8 levels with medical status in a population undergoing routine medical checkups: A cross-sectional study
- J. Morinaga, J. Zhao, +10 authors Y. Oike
- Medicine
- PloS one
- 14 March 2018
Purpose Angiopoietin-like proteins (ANGPTLs) 3, 4, and 8 reportedly contribute to progression of metabolic disease, a risk factor for cardiovascular disease (CVD). The purpose of this study was to… Expand
Hepatic Lipase: a Comprehensive View of its Role on Plasma Lipid and Lipoprotein Metabolism.
- J. Kobayashi, K. Miyashita, K. Nakajima, H. Mabuchi
- Chemistry, Medicine
- Journal of atherosclerosis and thrombosis
- 21 July 2015
Hepatic lipase (HL) is a key enzyme catalyzing the hydrolysis of triglycerides (TG) and phospholipids (PLs) in several lipoproteins. It is generally recognized that HL is involved in the remodeling… Expand
Synoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritis.
- T. Okada, Hiroto Tsukano, +9 authors Y. Oike
- Medicine
- The American journal of pathology
- 1 May 2010
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by symmetrical polyarticular synovitis of the diarthrodial joints. Several proinflammatory cytokines derived from both… Expand
Determination of plasma and urinary angiotensinogen levels in rodents by newly developed ELISA.
- H. Kobori, A. Katsurada, +6 authors L. G. Navar
- Chemistry, Medicine
- American journal of physiology. Renal physiology
- 1 May 2008
We recently reported that urinary excretion rates of angiotensinogen provide a specific index of the intrarenal renin-angiotensin system status in angiotensin II-dependent hypertensive rats.… Expand
Characterization of human thyrotropin receptor-related peptide-like immunoreactivity in peripheral blood of Graves' disease.
- M. Murakami, K. Miyashita, M. Yamada, T. Iriuchijima, M. Mori
- Chemistry, Medicine
- Biochemical and biophysical research…
- 31 July 1992
An antiserum raised against an alignment of amino acid-(32-56), termed TSHRP-1, in the extracellular domain of human thyrotropin (TSH) receptor was used to identify the TSH receptor-like substance in… Expand
Preferential expression of CD134, an HHV-6 cellular receptor, on CD4T cells in drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS).
- F. Miyagawa, Yuki Nakamura, +10 authors H. Asada
- Medicine
- Journal of dermatological science
- 1 August 2016