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Distinctive microRNA profiles relating to patient survival in esophageal squamous cell carcinoma.
The results indicate that microRNA expression profiles are important diagnostic and prognostic markers of esophageal cancer, which might be analyzed simply using economical approaches such as reverse transcription-PCR. Expand
A 5-MicroRNA Signature for Lung Squamous Cell Carcinoma Diagnosis and hsa-miR-31 for Prognosis
A new diagnostic microRNA classifier for SCC among Chinese patients and a new prognostic biomarker, hsa-miR-31 are identified. Expand
MicroRNAs‐372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B
This study revealed that miRNA (miRs‐372/373) can promote HBV expression through a pathway involving the transcription factor (NFIB) and provides new insights into the molecular basis in HBV and host interaction. Expand
Expression, regulation and roles of miR‐26a and MEG3 in tongue squamous cell carcinoma
- Ling-fei Jia, Su-bi Wei, +5 authors Guang-yan Yu
- Biology, Medicine
- International journal of cancer
- 15 November 2014
Assays in the human TSCC cell lines SCC‐15 and CAL27 showed that miR‐26a targets the DNA methyltransferase 3B transcript and that its inhibition may result in the upregulation of MEG3, providing a plausible link between the observed reduction of miR-26a and M EG3 in TSCC tissue. Expand
MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways
Mouse experiments revealed that upregulation of miR-133b in cervical carcinoma cells strongly promotes both in vivo tumorigenesis and independent metastasis to the mouse lung, and data indicates that up regulation ofmiR- 133b shortens the latency of cervical carcinomas. Expand
Rapid, accurate determination of multidrug resistance in M. tuberculosis isolates and sputum using a biochip system.
- Y. Guo, Y. Zhou, +11 authors Yanlin Zhao
- The international journal of tuberculosis and…
- 1 July 2009
The biochip system provides a simple, rapid, reliable and accurate clinical assay for the parallel detection of M. tuberculosis and prevalent MDR-TB in a 6 h procedure, using either culture isolates or sputum samples for diagnosis. Expand
Discovery of genes associated with fruit ripening in Carica papaya using expressed sequence tags
To identify genes involved in papaya fruit ripening, a total of 1171 expressed sequence tags were generated from randomly selected clones of two independent fruit cDNA libraries derived from yellow and red-fleshed fruit varieties with significant similarity to genes associated with fruit softening, aroma and colour biosynthesis. Expand
Integration of single oocyte trapping, in vitro fertilization and embryo culture in a microwell-structured microfluidic device.
A novel microwell-structured microfluidic device that integrates single oocyte trapping, fertilization and subsequent embryo culture is reported that may bring several advantages to IVF practices by simplifying oocyte handling and manipulation, allowing rapid and convenient medium changing, and enabling automated tracking of any single embryo development. Expand
A simulated annealing algorithm for finding consensus sequences
This paper describes a new algorithm for finding a consensus sequence, using the popular optimization method known as simulated annealing, and presents results demonstrating the high quality of the consensus sequences and alignments produced by the new algorithm. Expand
Patterns of histone acetylation.
- A. Thorne, D. Kmiciek, K. Mitchelson, P. Sautière, C. Crane-Robinson
- Biology, Medicine
- European journal of biochemistry
- 1 November 1990
Study of the specificity of site utilisation in the monoacetyl, diacetyl and triacetyl forms of histones H3, H4 and H2B reinforces the view that lysine acetylation in core histones is a very specific phenomenon that plays several functionally distinct roles. Expand